Numerical Simulation of the Diffusion of an Electroactive Molecule in Biosimilar Hydrogel Media

Abstract

Based on the experimental data of cyclic voltammetry, the diffusion coefficients of toluidine blue in alginate and gelatin hydrogels, as well as in their combinations, were determined. Using the experimental coefficients in the digital model, calculations of the reduction currents were carried out, which showed compliance with the experimental results. It is proposed to use the time when the current reaches a stationary level as an indicator of the diffusion properties of a hydrogel medium. The results are to be used to develop methods for evaluating the diffusion properties of hydrogel media, that is, bioinks and tissue engineering structures.