Complications after fine-needle aspiration cytology and core-needle biopsy in benign head & neck neoplasms

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola Pub Date : 2025-03-01 DOI:10.1016/j.otorri.2024.09.002

Alfonso Rodriguez-Urzay , Maria Landa-Garmendia , Jon Alexander Sistiaga-Suarez , Jose Angel González-Garcá , Ehkiñe Larruscain-Sarasola , Mikel Beristain , Carlos Miguel Chiesa-Estomba

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引用次数: 0

Abstract

Introduction

Benign neck masses are one of the most common causes of clinical consultation in head & neck (H&N) clinics. Fine needle aspiration cytology (FNAC) and core needle biopsy (CNB) have become among the main strategies for the diagnostic work-up of palpable and non-palpable neck lumps. Moreover, numerous studies have established the safety, high diagnostic yield, and added value of image-guided H&N biopsies, which play an important role in diagnosis, staging, and treatment planning, and can obviate the need for surgery for many patients. Nonetheless, despite the success of both techniques, there is a lack of recent studies regarding their safety and associated complication rates.

Material & method

A retrospective analysis was performed of prospective data on patients undergoing ultrasound-guided FNAC or CNB for benign H&N disease (e.g., salivary gland benign tumors, branchial cleft cyst, thyroglossal duct, cyst, lipoma, or neurinoma) between June 2016 and June 2021 in a tertiary university hospital.

Results

Overall, 192 patients were included (105 [54.7%] men and 87 [45.3%] women). The Kolmogorov-Smirnov test indicated that our data were normally distributed (p = 0.452). The mean age of enrolled patients was 54 ± 10 (range: 18–87). The anatomical site most commonly affected was a major salivary gland (74%). Regarding incidence and type of complications, nine (4.7%) patients experienced complications, infection being the most common problem. The risk of complications was highest in patients with branchial cleft cysts who had undergone FNAC (p = 0.028). Overall, the risk of complications was not associated with the type of technique (p = 0.603; OR: 0.942; 95% confidence interval = 0.245–3.624).

Conclusion

According to our results, FNAC and CNB are generally safe and reliable procedures in the diagnostic work-up of H&N lumps. Nevertheless, physicians should be aware of certain risks associated with these procedures.

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良性头颈部肿瘤细针穿刺细胞学及芯针活检术后并发症分析

颈部良性肿块是临床求诊的最常见原因之一。颈部（H&；N）诊所细针抽吸细胞学（FNAC）和核心针活检（CNB）已成为可触及和不可触及颈部肿块诊断工作的主要策略。此外，大量研究表明，图像引导下的H&；N活检具有安全性、高诊断率和附加价值，在诊断、分期和治疗计划中发挥着重要作用，许多患者无需手术。然而，尽管这两种技术都取得了成功，但最近缺乏关于其安全性和相关并发症发生率的研究。材料,方法回顾性分析2016年6月至2021年6月某三级大学附属医院超声引导下行H&；N良性疾病（如唾液腺良性肿瘤、鳃裂囊肿、甲状舌管、囊肿、脂肪瘤、神经鞘瘤）FNAC或CNB的前瞻性资料。结果共纳入192例患者，其中男性105例（54.7%），女性87例（45.3%）。Kolmogorov-Smirnov检验表明我们的数据是正态分布（p = 0.452）。入组患者的平均年龄为54±10岁（范围18-87岁）。最常受影响的解剖部位是大唾液腺（74%）。关于并发症的发生率和类型，9例（4.7%）患者出现并发症，感染是最常见的问题。鳃裂囊肿行FNAC的患者出现并发症的风险最高（p = 0.028）。总的来说，并发症的风险与手术方式无关(p = 0.603；OR: 0.942;95%置信区间= 0.245-3.624)。结论FNAC和CNB是诊断H&；N肿块安全可靠的检查方法。然而，医生应该意识到与这些手术相关的某些风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta otorrinolaringologica espanola OTORHINOLARYNGOLOGY-

CiteScore

1.40

自引率

20.00%

发文量

审稿时长

44 days

期刊介绍： Es la revista más importante en español dedicada a la especialidad. Ofrece progresos científicos y técnicos tanto a nivel de originales como de casos clínicos. Además, es la Publicación Oficial de la Sociedad Española de Otorrinolaringología y Patología Cérvico-Facial y está presente en los más prestigiosos índices de referencia.