Sustainable extraction of bioactive compounds from Vismia guianensis based on the principles of green chemistry

IF 3.4 3区工程技术 Q2 CHEMISTRY, PHYSICAL

Journal of Supercritical Fluids Pub Date : 2025-02-24 DOI:10.1016/j.supflu.2025.106562

Kriptsan Abdon Poletto Diel , Leandro Martins Siqueira , Pablo Pitol Silveira , Júlia Maier Labes , Mariana Koetz , Lucas Cardoso Marinho , Eduardo Cassel , Rubem Mário Figueiró Vargas , Gilsane Lino von Poser

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Abstract

Vismia guianensis (Aubl.) Choisy (Hypericaceae), a medicinal plant prevalent in the Amazon Forest region, presents anthraquinones as the main compounds. This study aims to compare the chemical composition of extracts obtained using organic solvents and supercritical CO₂ (scCO₂) under varying conditions. Additionally, mathematical models were applied to predict extraction kinetics. The results indicated that the extracts contained vismiaquinone A and physcion, among other minor anthraquinones, with scCO₂ proving to be more efficient in extracting both compounds. Notably, scCO₂ exhibited a higher selectivity for vismiaquinone A, yielding remarkably greater amounts. The mathematical modeling confirmed the consistency between the response surface method and the experimental data. In addition to demonstrating the effectiveness of an environmentally friendly extraction method, this research aims to add value to a medicinal plant widely used in Brazil, yet underexplored for its pharmacological and economic potential.

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来源期刊

Journal of Supercritical Fluids 工程技术-工程：化工

CiteScore

7.60

自引率

10.30%

发文量

236

审稿时长

56 days

期刊介绍： The Journal of Supercritical Fluids is an international journal devoted to the fundamental and applied aspects of supercritical fluids and processes. Its aim is to provide a focused platform for academic and industrial researchers to report their findings and to have ready access to the advances in this rapidly growing field. Its coverage is multidisciplinary and includes both basic and applied topics. Thermodynamics and phase equilibria, reaction kinetics and rate processes, thermal and transport properties, and all topics related to processing such as separations (extraction, fractionation, purification, chromatography) nucleation and impregnation are within the scope. Accounts of specific engineering applications such as those encountered in food, fuel, natural products, minerals, pharmaceuticals and polymer industries are included. Topics related to high pressure equipment design, analytical techniques, sensors, and process control methodologies are also within the scope of the journal.