Challenges and opportunities for AMR research in the ASEAN following the One Health approach

IF 4.1 2区医学 Q1 INFECTIOUS DISEASES

One Health Pub Date : 2025-02-27 DOI:10.1016/j.onehlt.2025.101001

Harish Kumar Tiwari , Daniel K.Y. Tan , Chhe Chinda , Duong Nu Tra My , Ha Thi Thu Hoang , Khao Keonam , Luu Quynh Huong , Ly Chanvatanak , Mot Virak , Nguyen Thuy Tram , Nittakone Soulinthone , Pham Duc Phuc , Thi Thu Hoai Nguyen , Vu Thi Thu Tra , Justin Beardsley

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引用次数: 0

Abstract

Background

Antimicrobial resistance (AMR) has emerged as a significant global challenge and Southeast Asia with rapid economic and population growth faces substantial challenge in dealing with emerging infectious diseases and antimicrobial resistance. Here we present the recommendations of a workshop that explored the challenges and opportunities for One Health approach towards AMR research in three countries of AEAN, namely, Cambodia, Laos, and Vietnam.

Methods

A workshop was organised in Hanoi, Vietnam in August 2023, involving participants involved in AMR research across varied sectors from three participating countries to prioritise the strategies that can be implemented in the region to fructify the One Health approach to tackle AMR. A modified Delphi approach was used to prioritise the top 10 Global Priority Research Questions for the region as developed by the Quadripartite (FAO, WHO, WOAH and UNEP). An iterative process was adopted to map priorities according to their impact and feasibility of application.

Results

Collaborative initiatives, such as a common platform for listing the research goals, a web-based surveillance mechanism, and an enhanced AMR awareness curricula were identified as the steps forward. A consensus statement highlighting the critical needs for improved technical and infrastructure capacity, collaboration between sectors, increased funding, and systematic data analysis was drafted.

Discussion

The participating countries have National Action Plans guided by the World Health Organization's Global Action Plan on AMR, but limited collaboration between human health and other sectors has impeded the benefits that One Health approach may achieve in the region. The recommendations include the need for improved technical and infrastructure capacity, and data collection across One Health sectors, besides increasing awareness at multiple levels.

Conclusion

A collaborative and coordinated effort to apply One Health initiatives for tackling AMR in the ASEAN region is imperative. The workshop formulated a roadmap for future direction by identifying priorities aimed at enhancing collaboration, addressing infrastructure gaps, and contributing to an effective intervention in the fight against AMR in the region.

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遵循“同一个健康”方针的东盟抗菌素耐药性研究的挑战和机遇

抗生素耐药性（AMR）已成为一项重大的全球挑战，经济和人口快速增长的东南亚在应对新发传染病和抗菌素耐药性方面面临重大挑战。在此，我们提出了一个研讨会的建议，该研讨会探讨了在东盟三个国家（即柬埔寨、老挝和越南）采用“一个健康”方法进行抗菌素耐药性研究的挑战和机遇。方法于2023年8月在越南河内组织了一次研讨会，来自三个参与国的不同部门参与抗微生物药物耐药性研究的与会者将优先考虑可在该地区实施的战略，以实现“同一个健康”方法来解决抗微生物药物耐药性问题。采用改进的德尔菲方法确定了四方（粮农组织、世卫组织、世界卫生组织和环境规划署）为该区域制定的十大全球重点研究问题的优先次序。采用了一个迭代过程，根据其影响和应用的可行性来确定优先事项。结果协作倡议，如列出研究目标的共同平台、基于网络的监测机制和增强抗微生物药物耐药性意识的课程，被确定为前进的步骤。会议起草了一份共识声明，强调了对改进技术和基础设施能力、部门间合作、增加资金和系统数据分析的迫切需求。讨论参与国制定了以世界卫生组织抗微生物药物耐药性全球行动计划为指导的国家行动计划，但人类健康部门与其他部门之间的合作有限，阻碍了“一个健康”办法在本区域可能实现的效益。这些建议包括需要改进技术和基础设施能力，以及在“同一个卫生”各部门收集数据，此外还需要在多个层面提高认识。必须进行协作和协调努力，在东盟地区实施“一个健康”倡议，以解决抗生素耐药性问题。研讨会制定了未来方向的路线图，确定了旨在加强合作、解决基础设施差距和促进有效干预该地区抗抗生素耐药性斗争的优先事项。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

One Health Medicine-Infectious Diseases

CiteScore

8.10

自引率

4.00%

发文量

审稿时长

18 weeks

期刊介绍： One Health - a Gold Open Access journal. The mission of One Health is to provide a platform for rapid communication of high quality scientific knowledge on inter- and intra-species pathogen transmission, bringing together leading experts in virology, bacteriology, parasitology, mycology, vectors and vector-borne diseases, tropical health, veterinary sciences, pathology, immunology, food safety, mathematical modelling, epidemiology, public health research and emergency preparedness. As a Gold Open Access journal, a fee is payable on acceptance of the paper. Please see the Guide for Authors for more information. Submissions to the following categories are welcome: Virology, Bacteriology, Parasitology, Mycology, Vectors and vector-borne diseases, Co-infections and co-morbidities, Disease spatial surveillance, Modelling, Tropical Health, Discovery, Ecosystem Health, Public Health.