Efficacy of Ayurvedic treatment given to cancer patients in the prevention of COVID-19 – A Retrospective Cohort Study at Integrated Cancer Treatment and Research Centre, Wagholi

IF 1.7 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE

Journal of Ayurveda and Integrative Medicine Pub Date : 2025-03-01 DOI:10.1016/j.jaim.2024.101045

Sadanand Sardeshmukh, Vineeta Deshmukh, Vidya Gupta, Vasanti Godse, Shweta Gujar, Swapna Kulkarni, Sneha Dalvi, Nilambari Sardeshmukh, Bhagyashree Sardeshmukh, Sushama Bhuvad, Sandeep Chavan, Vinita Awalkanthe, Shrinivas Datar, Anita Shingte, Abhishek Salunkhe, Amruta Salunkhe, Sneha Nabar, Dhananjay Deshpande, Trupti Dafare

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引用次数: 0

Abstract

Background

Cancer patients are considered to have a higher risk of developing severe Coronavirus Disease 2019 (COVID-19) and a higher mortality rate. Moreover, poor prognosis observed in them is associated with multiple co-morbidities. Ayurveda can prove to be effective in preventing COVID-19 as well as improving clinical outcomes against COVID-19 in cancer patients.

Objectives

To evaluate the effect of Ayurvedic treatments given to cancer patients as also a preventive modality against COVID-19 infections.

Methods

700 cancer patients were enrolled in the study. The demographic information regarding their age, sex, organs involved, stage, pre-existing comorbidities, Karnofsky score, addictions, undergoing conventional cancer treatment, type of conventional treatment, and duration of Ayurvedic cancer treatment was collected from the institutional records. These patients were interviewed telephonically or in person to obtain information related to their COVID-19 status from March 2020 to Sep 2021, which included a) whether they were affected with COVID-19 or not, b) If affected, the severity of COVID-19 symptoms, c) vaccination status, d) mortality, and e) if in contact with relative affected by COVID-19.

Results

The surveyed cohort had 56 years as the median age, more female patients, Karnofsky score between 80 and 100, and hypertension as well as diabetes as major co-morbidities. During the 1st and 2nd waves, 34 (4.85%) and 65 patients (10.09 %) were COVID-19 positive while 4.91 % and 11.11% of patients with addictions were covid positive, respectively, the rest remained unaffected.

There was no specific trend in % of COVID-19-positive cancer patients concerning stage, but those with stage IV undergoing conventional treatment showed increased prevalence (p < 0.001). Prolonged Ayurvedic treatment exhibited a decreasing trend in % COVID-19 positive patients, which is highly significant (p < 0.001). Specifically, those undergoing conventional therapy, and also received Ayurvedic treatment simultaneously for more than 3 years remained unaffected by COVID-19, which was statistically significant in both waves (p < 0.001).

Conclusion

Ayurvedic treatments given to cancer patients are effective in preventing COVID-19 infections in these patients.

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阿育吠陀治疗对癌症患者预防COVID-19的疗效——Wagholi癌症综合治疗和研究中心的回顾性队列研究

癌症患者被认为患2019年严重冠状病毒病（COVID-19）的风险更高，死亡率也更高。此外，预后不良与多种合并症有关。阿育吠陀可以有效预防COVID-19，并改善癌症患者对COVID-19的临床结果。目的评价阿育吠陀治疗对癌症患者预防COVID-19感染的效果。方法选取700例肿瘤患者作为研究对象。从机构记录中收集了患者的年龄、性别、涉及的器官、分期、已存在的合并症、Karnofsky评分、成瘾、接受常规癌症治疗、常规治疗类型和阿育吠陀癌症治疗持续时间等人口统计信息。对这些患者进行电话或当面访谈，以获取其2020年3月至2021年9月期间COVID-19状况的相关信息，包括a)是否感染COVID-19， b)如果感染，COVID-19症状的严重程度，c)疫苗接种状况，d)死亡率，以及e)是否与感染COVID-19的亲属接触。结果调查队列中位年龄为56岁，女性患者较多，Karnofsky评分在80 ~ 100之间，高血压和糖尿病为主要合并症。在第一波和第二波中，34例（4.85%）和65例（10.09%）患者呈covid -19阳性，成瘾患者中分别有4.91%和11.11%呈covid阳性，其余患者未受影响。covid -19阳性癌症患者的百分比与分期没有特定的趋势，但接受常规治疗的IV期患者的患病率增加(p <；0.001)。延长阿育吠陀治疗在% COVID-19阳性患者中呈下降趋势，具有高度显著性(p <；0.001)。具体而言，接受常规治疗和同时接受阿育吠陀治疗超过3年的患者未受COVID-19影响，这在两波中均具有统计学意义(p <；0.001)。结论阿育吠陀治疗可有效预防癌症患者新冠肺炎感染。

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