Optimized PEG/eudragit-Zn4V2O9 nanostructures for effective catalytic and antibacterial activity with computational insights

IF 4.1 3区化学 Q2 CHEMISTRY, PHYSICAL

Journal of Photochemistry and Photobiology A-chemistry Pub Date : 2025-03-01 DOI:10.1016/j.jphotochem.2025.116365

Muhammad Ahmad , Ali Haider , Iram Shahzadi , Anwar Ul-Hamid , Muhammad Imran , Muhammad Ali Khan , Ghafar Ali , Mohamed Mohamed Soliman , Muhammad Ikram

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引用次数: 0

Abstract

A low-temperature co-precipitation approach was used to synthesize polyethylene glycol (PEG) and eudragit (Eud) doped zinc vanadate (Zn₄V₂O₉) for effective methyl orange dye reduction and antibacterial activity. This study aimed to increase the catalytic and antibacterial efficacy of Zn₄V₂O₉, by providing more active sites, and charge transfer efficacy with dopants. Varying concentrations of PEG were doped into Eud-Zn₄V₂O₉, 3 % PEG/Eud-Zn₄V₂O₉ was optimized for catalytic activity and 6 % PEG/Eud-Zn₄V₂O₉ was optimized for antibacterial activity. Comprehensive characterizations revealed monoclinic crystal structure, polycrystalline behavior, reduced bandgap energy, and multiple morphologies of PEG/Eud-Zn₄V₂O₉. The optimized sample showed 97.85 % degradation of methyl orange with a reducing agent without the presence of light. 6 % PEG/Eud-Zn₄V₂O₉ proved to be an effective to be an effective antibacterial agent (inhibition zone 6.55 ± 0.02) against S. aureus. The docking analysis of Eud-doped Zn₄V₂O₉ and PEG/Eud-doped Zn₄V₂O₉ laid out the suppressive effects of DNA gyrase enzyme in S. aureus, besides their antibacterial properties.

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来源期刊

Journal of Photochemistry and Photobiology A-chemistry 化学-物理化学

CiteScore

7.90

自引率

7.00%

发文量

580

审稿时长

48 days

期刊介绍： JPPA publishes the results of fundamental studies on all aspects of chemical phenomena induced by interactions between light and molecules/matter of all kinds. All systems capable of being described at the molecular or integrated multimolecular level are appropriate for the journal. This includes all molecular chemical species as well as biomolecular, supramolecular, polymer and other macromolecular systems, as well as solid state photochemistry. In addition, the journal publishes studies of semiconductor and other photoactive organic and inorganic materials, photocatalysis (organic, inorganic, supramolecular and superconductor). The scope includes condensed and gas phase photochemistry, as well as synchrotron radiation chemistry. A broad range of processes and techniques in photochemistry are covered such as light induced energy, electron and proton transfer; nonlinear photochemical behavior; mechanistic investigation of photochemical reactions and identification of the products of photochemical reactions; quantum yield determinations and measurements of rate constants for primary and secondary photochemical processes; steady-state and time-resolved emission, ultrafast spectroscopic methods, single molecule spectroscopy, time resolved X-ray diffraction, luminescence microscopy, and scattering spectroscopy applied to photochemistry. Papers in emerging and applied areas such as luminescent sensors, electroluminescence, solar energy conversion, atmospheric photochemistry, environmental remediation, and related photocatalytic chemistry are also welcome.