Unveiling the contribution mechanism and the role of oxygen vacancies in the simultaneous electrochemical sensing of ceftriaxone and diclofenac by CPE/zeolite

IF 5.3 3区材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY

Materials Research Bulletin Pub Date : 2025-02-23 DOI:10.1016/j.materresbull.2025.113398

Amir Khosravi-Hamoleh , Raziyeh Taban , Mohsen Cheraghizade

{"title":"Unveiling the contribution mechanism and the role of oxygen vacancies in the simultaneous electrochemical sensing of ceftriaxone and diclofenac by CPE/zeolite","authors":"Amir Khosravi-Hamoleh , Raziyeh Taban , Mohsen Cheraghizade","doi":"10.1016/j.materresbull.2025.113398","DOIUrl":null,"url":null,"abstract":"<div><div>This study introduces a carbon paste electrode modified with zeolite (CPE/zeolite) as an effective electrochemical sensor for the simultaneous detection of Ceftriaxone (Cef) and Diclofenac (Dic). The sensor's performance was evaluated in a mixed supporting electrolyte of 0.1 M phosphoric acid and 0.1 M sodium hydroxide. The role of oxygen vacancies (O<sub>v</sub>) in electrochemical sensing was investigated. Under optimized conditions, the sensor demonstrated excellent sensitivity with a linear detection range of 1–100 µM for both analytes and limits of detection (LOD) of 1 µM for Cef and Dic. The CPE/zeolite sensor showed reliable recovery rates (97.8–99.2 %) in real human blood and urine samples. This study highlights the significant role of zeolite in enhancing electrode performance by providing a high surface area and facilitating charge transfer through O<sub>v</sub>-mediated mechanisms. The CPE/zeolite sensor offers a cost-effective, stable, and sensitive platform for real-time pharmaceutical monitoring and environmental applications.</div></div>","PeriodicalId":18265,"journal":{"name":"Materials Research Bulletin","volume":"188 ","pages":"Article 113398"},"PeriodicalIF":5.3000,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Materials Research Bulletin","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0025540825001060","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

This study introduces a carbon paste electrode modified with zeolite (CPE/zeolite) as an effective electrochemical sensor for the simultaneous detection of Ceftriaxone (Cef) and Diclofenac (Dic). The sensor's performance was evaluated in a mixed supporting electrolyte of 0.1 M phosphoric acid and 0.1 M sodium hydroxide. The role of oxygen vacancies (O_v) in electrochemical sensing was investigated. Under optimized conditions, the sensor demonstrated excellent sensitivity with a linear detection range of 1–100 µM for both analytes and limits of detection (LOD) of 1 µM for Cef and Dic. The CPE/zeolite sensor showed reliable recovery rates (97.8–99.2 %) in real human blood and urine samples. This study highlights the significant role of zeolite in enhancing electrode performance by providing a high surface area and facilitating charge transfer through O_v-mediated mechanisms. The CPE/zeolite sensor offers a cost-effective, stable, and sensitive platform for real-time pharmaceutical monitoring and environmental applications.

Abstract Image

查看原文本刊更多论文

揭示了氧空位在CPE/沸石对头孢曲松和双氯芬酸同时电化学传感中的贡献机制和作用

本研究介绍了一种沸石修饰的碳糊电极（CPE/沸石）作为同时检测头孢曲松（Cef）和双氯芬酸（Dic）的有效电化学传感器。在0.1 M磷酸和0.1 M氢氧化钠的混合支撑电解质中对传感器的性能进行了评价。研究了氧空位（Ov）在电化学传感中的作用。在优化条件下，该传感器表现出优异的灵敏度，对两种分析物的线性检测范围为1 - 100µM，对Cef和Dic的检出限（LOD）为1µM。CPE/沸石传感器在真实人体血液和尿液样品中具有可靠的回收率（97.8 - 99.2%）。该研究强调了沸石在提高电极性能方面的重要作用，通过提供高表面积和通过ov介导的机制促进电荷转移。CPE/沸石传感器为实时药物监测和环境应用提供了一个经济、稳定和敏感的平台。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Materials Research Bulletin 工程技术-材料科学：综合

CiteScore

9.80

自引率

5.60%

发文量

372

审稿时长

42 days

期刊介绍： Materials Research Bulletin is an international journal reporting high-impact research on processing-structure-property relationships in functional materials and nanomaterials with interesting electronic, magnetic, optical, thermal, mechanical or catalytic properties. Papers purely on thermodynamics or theoretical calculations (e.g., density functional theory) do not fall within the scope of the journal unless they also demonstrate a clear link to physical properties. Topics covered include functional materials (e.g., dielectrics, pyroelectrics, piezoelectrics, ferroelectrics, relaxors, thermoelectrics, etc.); electrochemistry and solid-state ionics (e.g., photovoltaics, batteries, sensors, and fuel cells); nanomaterials, graphene, and nanocomposites; luminescence and photocatalysis; crystal-structure and defect-structure analysis; novel electronics; non-crystalline solids; flexible electronics; protein-material interactions; and polymeric ion-exchange membranes.