Monitoring of hepatitis B infection in the elderly population of eastern Iran

Q3 Medicine

Vacunas Pub Date : 2025-01-01 DOI:10.1016/j.vacun.2024.08.002

Abdol Sattar Pagheh , Effat Alemzadeh , Eisa Nazar , Mitra Moodi , Farshad Sharifi , Ebrahim Miri-Moghaddam , Mohamad Taghi Rahimi , Soroush Mohammadi , Masood Ziaee

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引用次数: 0

Abstract

Objectives

This study aimed to investigate the prevalence of HBV infection and its associated risk factors in the elderly in Birjand.

Materials and methods

The present study was a part of the community-based prospective cohort study. Subjects over 60 years of age were assessed using standard questionnaires and blood factors. The samples were tested for HBsAg by enzyme-linked immunosorbent assay.

Results

Of 542 elderly people living in Birjand, 11 cases (2.03%) were positive. The median age of patients with HBsAg positive and negative was 69 (IQR: 63–77) years and 67 (IQR: 63–74) years, respectively. The results of the multiple logistic regression model showed that fatty liver disease was significantly associated with having hepatitis B (AOR (95% CI)=5.50 (1.16, 25.88)) (p < .05). However, there was no significant relationship found between variables age, sex, marital status, years of study, underlying diseases, body mass index, smoking, and blood factors with having hepatitis B (p > .05).

Conclusions

Even though there were only a few positive cases, leading to a non-significant report, it is crucial to emphasize the clinical significance and health and well-being of elderly individuals contracting hepatitis B. This information can be valuable in devising suitable disease management strategies for this age group.

查看原文本刊更多论文

伊朗东部老年人群乙型肝炎感染监测

目的调查英国老年人HBV感染的流行情况及其相关危险因素。材料和方法本研究是社区前瞻性队列研究的一部分。60岁以上 岁的受试者使用标准问卷和血液因子进行评估。采用酶联免疫吸附法检测HBsAg。结果542例老年人中，11例（2.03%）呈阳性。HBsAg阳性和阴性患者的中位年龄分别为69 （IQR: 63-77）岁和67 （IQR: 63-74）岁。多元logistic回归模型结果显示，脂肪肝与乙型肝炎显著相关(AOR (95% CI)=5.50 (1.16, 25.88)) (p <；. 05)。然而，年龄、性别、婚姻状况、学习年限、潜在疾病、体重指数、吸烟和血液因素与乙型肝炎之间没有显著关系(p >；. 05)。结论虽然报告的阳性病例较少，但重视老年人乙肝感染的临床意义和健康状况对制定适合该年龄组的疾病管理策略具有重要意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Vacunas Medicine-Infectious Diseases

CiteScore

3.90

自引率

0.00%

发文量

138

审稿时长

62 days

期刊介绍： Sin duda una de las mejores publicaciones para conocer los avances en el campo de las vacunaciones preventivas, tanto en el ámbito de la investigación básica como aplicada y en la evaluación de programas de vacunaciones. Su alta calidad y utilidad la ha llevado a estar indexada en los prestigiosos índices IME y SCOPUS.