The Impact of Place of Residence on Antiretroviral Therapy Adherence: A Systematic Review and Meta-Analysis.

IF 1.1 Q4 INFECTIOUS DISEASES
AIDS Research and Treatment Pub Date : 2025-02-22 eCollection Date: 2025-01-01 DOI:10.1155/arat/5757907
Oluwaseun Abdulganiyu Badru, Joy Chioma Edeh, Rita Ifeyinwa Okonkwo, Luchuo Engelbert Bain, Oluwafemi Atanda Adeagbo
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引用次数: 0

Abstract

Objective: There is evidence of geographical variation in HIV coverage and antiretroviral therapy (ART) adherence, and studies have investigated how the place of residence of people living with HIV (PLWH) influences ART adherence. Where people reside influences their access to health care. Studies on the influence of place of residence on ART adherence among PLWH in Nigeria have been reported in the literature. However, no review has synthesized these findings. Against this backdrop, this review seeks to determine whether adherence to ART differs by place of residence in Nigeria. Methods: In May 2024, we searched four databases (CINAHL Plus, PubMed, Scopus, and Web of Science). Only empirical studies with a test of association between place of residence (i.e., urban and rural) and adherence to ART were included. We performed a fixed-effect meta-analysis with the meta package on R Studio Version 4.2.0. Results: We included six of the 91 articles across the four databases. Most studies (n = 5) were conducted in the Southern region. The assessment of place of residence and adherence varies across the studies. We found that PLWH who reside in urban areas were 20% more likely to adhere to ART compared to those who live in rural areas (odds ratio: 1.20; 95% confidence interval: 1.01-1.43). Similarly, PLWH in the South-South region of Nigeria and reside in the urban areas were 1.27 (95% CI: 1.01-1.58) more likely to adhere to ART than those living in the rural areas. This observation was insignificantly true for the South-East region. Conclusion: PLWH who reside in urban areas may better adhere to ART than their counterparts living in rural areas. Non-governmental organizations and government agencies working with PLWH should prioritize those living in rural areas because they are more likely to face greater barriers to adherence.

居住地对抗逆转录病毒治疗依从性的影响:一项系统回顾和荟萃分析。
目的:有证据表明艾滋病毒覆盖率和抗逆转录病毒治疗(ART)依从性存在地理差异,研究调查了艾滋病毒感染者(PLWH)的居住地如何影响抗逆转录病毒治疗依从性。人们居住的地方影响着他们获得卫生保健的机会。文献报道了尼日利亚PLWH患者居住地对抗逆转录病毒治疗依从性影响的研究。然而,没有综述综合了这些发现。在此背景下,本审查旨在确定在尼日利亚,抗逆转录病毒治疗依从性是否因居住地而异。方法:于2024年5月检索4个数据库(CINAHL Plus、PubMed、Scopus和Web of Science)。仅纳入了检验居住地(即城市和农村)与抗逆转录病毒治疗依从性之间关系的实证研究。我们使用R Studio 4.2.0版本上的元包进行了固定效应元分析。结果:我们在四个数据库中收录了91篇文章中的6篇。大多数研究(n = 5)在南部地区进行。对居住地和依从性的评估在不同的研究中有所不同。我们发现,与生活在农村地区的人相比,居住在城市地区的PLWH坚持抗逆转录病毒治疗的可能性高出20%(优势比:1.20;95%置信区间:1.01-1.43)。同样,居住在尼日利亚南南地区和城市地区的PLWH比居住在农村地区的PLWH坚持抗逆转录病毒治疗的可能性高1.27% (95% CI: 1.01-1.58)。这一观察结果在东南地区并不明显。结论:居住在城市地区的艾滋病妇女比居住在农村地区的艾滋病妇女更能坚持抗逆转录病毒治疗。与PLWH合作的非政府组织和政府机构应优先考虑生活在农村地区的人,因为他们更有可能面临更大的遵守障碍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
AIDS Research and Treatment
AIDS Research and Treatment INFECTIOUS DISEASES-
CiteScore
3.10
自引率
0.00%
发文量
13
审稿时长
18 weeks
期刊介绍: AIDS Research and Treatment is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies focused on all aspects of HIV and AIDS, from the molecular basis of disease to translational and clinical research. In addition, articles relating to prevention, education, and behavior change will be considered
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