L Blokland, E de Kuijper-Timmermans, M de Kuijper, K Gooijer, G J Harsevoort, M C Zillikens, N M Appelman-Dijkstra, G J M Janus, S Kalaykova
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引用次数: 0
Abstract
Objective: This study investigated self-reported symptoms of temporomandibular disorders, mandibular functional impairment, and obstructive sleep apnea among Dutch adults with Osteogenesis Imperfecta.
Materials and methods: A cross-sectional online survey was distributed among Dutch adults with Osteogenesis Imperfecta. Possible risk factors for self-reported temporomandibular disorders (3Q/TMD; DC/TMD), mandibular impairments (Mandibular Function Impairment Questionnaire), and obstructive sleep apnea (STOP-Bang) were explored using univariate and multiple regression analyses.
Results: 31% of 155 respondents reported temporomandibular disorder symptoms and 40.0% and 5.2% moderate and severe mandibular function impairment, respectively. Intermediate and severe risk for obstructive sleep apnea were reported by 16.1% and 14.8%, respectively. Female gender and Osteogenesis Imperfecta type III were independently associated with the presence of self-reported temporomandibular disorders. Osteogenesis Imperfecta type III, missing teeth, and self-reported temporomandibular disorders were independently associated with impaired mandibular function. Higher age, male gender, and bisphonate use were independently associated with a higher risk for positive screening for obstructive sleep apnea.
Conclusions: A substantial proportion of Dutch adults with Osteogenesis Imperfecta reported symptoms indicative of temporomandibular disorders, mandibular function impairment, and higher risk for obstructive sleep apnea. Especially Osteogenesis Imperfecta type III patients are at risk for self-reported temporomandibular disorders and hampered mandibular function.
期刊介绍：
Oral Diseases is a multidisciplinary and international journal with a focus on head and neck disorders, edited by leaders in the field, Professor Giovanni Lodi (Editor-in-Chief, Milan, Italy), Professor Stefano Petti (Deputy Editor, Rome, Italy) and Associate Professor Gulshan Sunavala-Dossabhoy (Deputy Editor, Shreveport, LA, USA). The journal is pre-eminent in oral medicine. Oral Diseases specifically strives to link often-isolated areas of dentistry and medicine through broad-based scholarship that includes well-designed and controlled clinical research, analytical epidemiology, and the translation of basic science in pre-clinical studies. The journal typically publishes articles relevant to many related medical specialties including especially dermatology, gastroenterology, hematology, immunology, infectious diseases, neuropsychiatry, oncology and otolaryngology. The essential requirement is that all submitted research is hypothesis-driven, with significant positive and negative results both welcomed. Equal publication emphasis is placed on etiology, pathogenesis, diagnosis, prevention and treatment.
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