Accelerating spin-echo EPI through combined patterned multislice excitation and simultaneous multislice acquisition.

IF 3 3区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Jiazheng Zhou, Peter van Gelderen, Jacco A de Zwart, Yicun Wang, Jeff H Duyn
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引用次数: 0

Abstract

Purpose: To demonstrate further acceleration of spin echo MRI by combining the simultaneous multi-slice approach with the recently introduced patterned multislice excitation (PME) technique and evaluate application for rapid diffusion-weighted MRI.

Theory and methods: Implementation at 3T involved the design of RF pulses simultaneously acting on four separate slices within hardware limits on peak amplitude. This was accomplished by time-shifted sub-pulses and a dedicated switching scheme of the slice-select gradient. The new technique was evaluated on two clinical MRI systems with differing maximum gradient strength.

Results: Four-fold acceleration was successfully achieved by combining PME with rate-2 SMS. Within fixed measurement time, the proposed approach allows increased averaging or more elaborate sampling of diffusion tensor space. Depending on implementation, gains in SNR per unit time were modest or small, which is attributed to out-of-slice saturation effects of the RF pulses.

Conclusion: Combination of PME with SMS-2 for further acceleration of diffusion imaging is feasible at 3T.

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来源期刊
CiteScore
6.70
自引率
24.20%
发文量
376
审稿时长
2-4 weeks
期刊介绍: Magnetic Resonance in Medicine (Magn Reson Med) is an international journal devoted to the publication of original investigations concerned with all aspects of the development and use of nuclear magnetic resonance and electron paramagnetic resonance techniques for medical applications. Reports of original investigations in the areas of mathematics, computing, engineering, physics, biophysics, chemistry, biochemistry, and physiology directly relevant to magnetic resonance will be accepted, as well as methodology-oriented clinical studies.
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