Ryan Njeim, Mohammad Abureesh, Yashna Singh, Youssef El Douaihy
{"title":"Unexpected Discovery at Resection Site: Plasmablastic Lymphoma After Polypectomy.","authors":"Ryan Njeim, Mohammad Abureesh, Yashna Singh, Youssef El Douaihy","doi":"10.14309/crj.0000000000001633","DOIUrl":null,"url":null,"abstract":"<p><p>Plasmablastic lymphoma (PBL) is a rare, aggressive subtype of diffuse large B-cell lymphoma that has usually been associated with human immunodeficiency virus and Ebstein-Barr virus infections. Commonly seen in the oral cavity, it can affect any part of the gastrointestinal tract. This report describes a unique case of PBL that appeared in an 81-year-old immunocompetent patient. During an initial colonoscopy, a 2-cm polyp in the distal transverse colon was removed via full-thickness resection with pathology showing tubular adenoma with foci of high-grade dysplasia. After 7 months, a repeat colonoscopy found a 3-cm sessile polyp at the site of resection, which, after removal, was found to be a PBL. This is the first case described in the literature regarding the growth of PBL after full-thickness resection of a tubular adenoma in such a short interval.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01633"},"PeriodicalIF":0.6000,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11868435/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACG Case Reports Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14309/crj.0000000000001633","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Plasmablastic lymphoma (PBL) is a rare, aggressive subtype of diffuse large B-cell lymphoma that has usually been associated with human immunodeficiency virus and Ebstein-Barr virus infections. Commonly seen in the oral cavity, it can affect any part of the gastrointestinal tract. This report describes a unique case of PBL that appeared in an 81-year-old immunocompetent patient. During an initial colonoscopy, a 2-cm polyp in the distal transverse colon was removed via full-thickness resection with pathology showing tubular adenoma with foci of high-grade dysplasia. After 7 months, a repeat colonoscopy found a 3-cm sessile polyp at the site of resection, which, after removal, was found to be a PBL. This is the first case described in the literature regarding the growth of PBL after full-thickness resection of a tubular adenoma in such a short interval.
期刊介绍:
ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.