Efficacy of photodynamic therapy in controlling persistent scalp infections after temporal lifting: A case report

IF 3.1 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-02-27 DOI:10.1016/j.pdpdt.2025.104538

Priscila Fernanda Campos de Menezes , Vanderlei Salvador Bagnato

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引用次数: 0

Abstract

Photodynamic therapy (PDT) is a promising approach for treating infections caused by antibiotic-resistant microorganisms. This case report discusses the successful use of PDT in conjunction with antibiotics to treat a persistent scalp abscess in a patient. After multiple failed antibiotic treatments, PDT was introduced, resulting in significant improvement and eventual resolution of the infection. PDT was performed using a formulation of methylene blue in an oily base at 0.05%, applied intralesionally with an 18G cannula and also topically, followed by exposure to red LED light at 50 J/cm². The treatment resulted in the resolution of the infection after two sessions. This case highlights the potential of PDT as an adjunctive therapy in managing complex skin infections, reducing persistent inflammation, and combating bacterial resistance. Additionally, PDT is suggested as a preventive measure in the immediate postoperative period to avoid late complications that might require antibiotics, thereby reducing the risk of developing microbial resistance. Future studies should explore photosensitizers that do not cause skin staining, as can occur with methylene blue, particularly on the face.

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光动力疗法控制颞部提升术后持续性头皮感染的疗效：1例报告。

光动力疗法（PDT）是治疗抗生素耐药微生物引起的感染的一种很有前途的方法。本病例报告讨论了成功使用PDT联合抗生素治疗持续性头皮脓肿的病人。在多次抗生素治疗失败后，引入PDT，导致感染的显着改善和最终解决。PDT使用亚甲基蓝配方，在0.05%的油基中进行，局部应用18G套管，然后暴露在50 J/cm²的红色LED光下。经过两次治疗，感染得到了解决。该病例强调了PDT作为治疗复杂皮肤感染、减少持续性炎症和对抗细菌耐药性的辅助疗法的潜力。此外，建议在术后立即采取PDT预防措施，以避免可能需要抗生素的晚期并发症，从而降低发生微生物耐药的风险。未来的研究应该探索不会引起皮肤染色的光敏剂，因为亚甲蓝可能会引起皮肤染色，特别是在脸上。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.