Oral plasmacytoma in multiple myeloma patients: report of 18 cases.

IF 2 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-02-08 DOI:10.1016/j.oooo.2025.02.002

Lama Alabdulaaly, Maryam Jessri, Nathaniel Treister, Tiffany Tavares, Efstathios Pettas, Sook-Bin Woo, Jacob Laubach, Alessandro Villa

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引用次数: 0

Abstract

Objectives: Plasmacytoma is a malignant neoplasm of plasma cells with or without an underlying multiple myeloma (MM). Plasmacytoma rarely involves the oral mucosa and jaw bones. We aimed to describe oral plasmacytoma in MM patients.

Study design: Patients with oral plasmacytoma seen at the Oral Medicine clinic from 2007 to 2024 were included in this study.

Results: There were 18 patients (26 oral plasmacytomas). The median age was 60.5 years (72.3% females). The most common symptoms were pain and bleeding. Ten patients had gnathic involvement, and 8 patients had soft tissue disease without bony involvement. The gingiva was the most common site (50.0%) and buccolingual involvement was seen in 38.5% of cases. Treatment directed at the oral disease was rendered in 11 patients. Over 90% of patients died with a median of 5 months.

Conclusions: MM patients may present with oral involvement most commonly on the gingiva with frequent buccal and lingual involvement.

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来源期刊

Oral Surgery Oral Medicine Oral Pathology Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.80

自引率

6.90%

发文量

1217

审稿时长

2-4 weeks

期刊介绍： Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.