Precision Errors of Lower Leg Measurement by pQCT in Children With Medical Conditions: Bone Density, Mass, Dimensions, Mechanostat Parameters and Soft Tissue Composition.

IF 1.7 4区医学 Q4 NEUROSCIENCES

Journal of musculoskeletal & neuronal interactions Pub Date : 2025-03-01 DOI:10.22540/JMNI-25-018

Maciej Jaworski, Maria Kobylińska

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引用次数: 0

Abstract

Objectives: The one of the developing methods in paediatric densitometry field is peripheral quantitative computed tomography (pQCT), however, very little is known about its precision in children. The aim of presented study was to evaluate the precision errors for bone density, mass, dimensions, strength and mechanostat parameters as well as for soft tissue composition in children with medical conditions.

Methods: Stratec XCT 2000L apparatus was used. The measurement sites were 4%, 14%, 38% and 66% of the lower leg length. The study group comprised of 60 patients (30 girls) aged 5,0-18,0 yrs.

Results: Relative precision errors (CV%RMS) were from 0,25% for tibia 38% cortical bone density to 5,49% for fat cross-sectional area to muscle cross-sectional area ratio. Least significant change (LSC) was from 0,70% to 15,20%, respectively. Weak to moderate correlations between precision errors and body size, with r from -0,43 to 0,71, have been observed.

Conclusion: Presented study revealed pQCT method at the lower leg in children with medical conditions as relatively precise technique. Obtained results provides an attainable basis for design and interpretation of pQCT studies in children with medical conditions.

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通过 pQCT 对患有疾病的儿童进行小腿测量的精度误差：骨密度、质量、尺寸、力学参数和软组织成分。

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来源期刊

Journal of musculoskeletal & neuronal interactions NEUROSCIENCES-PHYSIOLOGY

CiteScore

3.40

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Journal of Musculoskeletal and Neuronal Interactions (JMNI) is an academic journal dealing with the pathophysiology and treatment of musculoskeletal disorders. It is published quarterly (months of issue March, June, September, December). Its purpose is to publish original, peer-reviewed papers of research and clinical experience in all areas of the musculoskeletal system and its interactions with the nervous system, especially metabolic bone diseases, with particular emphasis on osteoporosis. Additionally, JMNI publishes the Abstracts from the biannual meetings of the International Society of Musculoskeletal and Neuronal Interactions, and hosts Abstracts of other meetings on topics related to the aims and scope of JMNI.