{"title":"Comprehensive multifaceted approach in antibody therapeutics: targeting gut dysbiosis and gastrointestinal oncogenic cells.","authors":"Uddipta Guha","doi":"10.1007/s10787-025-01689-y","DOIUrl":null,"url":null,"abstract":"<p><p>Treatment of biomedicine has advanced significantly in recent years, and it now has a very high success rate with severity of side effects making it so much more compelling to study emerging treatments. A broad concept is proposed, which pools in nominal antibiotics administration nutrition nutritional supplement if requisite and antibodies by maximizing the potential synergy of these elements, that is where conventional methods stop, this paradigm shift starts. The antibiotics act on the pathogen alone and when combined with therapeutic techniques results in increased recovery along with proper body defenses. The first-ever study of its kind combines antibody complex disguising as a carrier for the drugs which improves the palatability, extend retention in body and makes easy to store as well as distribute. This ground-breaking method could really alter the way digestive diseases is treated and provide an alternative to conventional methods.</p>","PeriodicalId":13551,"journal":{"name":"Inflammopharmacology","volume":" ","pages":""},"PeriodicalIF":4.6000,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Inflammopharmacology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s10787-025-01689-y","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Treatment of biomedicine has advanced significantly in recent years, and it now has a very high success rate with severity of side effects making it so much more compelling to study emerging treatments. A broad concept is proposed, which pools in nominal antibiotics administration nutrition nutritional supplement if requisite and antibodies by maximizing the potential synergy of these elements, that is where conventional methods stop, this paradigm shift starts. The antibiotics act on the pathogen alone and when combined with therapeutic techniques results in increased recovery along with proper body defenses. The first-ever study of its kind combines antibody complex disguising as a carrier for the drugs which improves the palatability, extend retention in body and makes easy to store as well as distribute. This ground-breaking method could really alter the way digestive diseases is treated and provide an alternative to conventional methods.
期刊介绍：
Inflammopharmacology is the official publication of the Gastrointestinal Section of the International Union of Basic and Clinical Pharmacology (IUPHAR) and the Hungarian Experimental and Clinical Pharmacology Society (HECPS). Inflammopharmacology publishes papers on all aspects of inflammation and its pharmacological control emphasizing comparisons of (a) different inflammatory states, and (b) the actions, therapeutic efficacy and safety of drugs employed in the treatment of inflammatory conditions. The comparative aspects of the types of inflammatory conditions include gastrointestinal disease (e.g. ulcerative colitis, Crohn''s disease), parasitic diseases, toxicological manifestations of the effects of drugs and environmental agents, arthritic conditions, and inflammatory effects of injury or aging on skeletal muscle. The journal has seven main interest areas:
-Drug-Disease Interactions - Conditional Pharmacology - i.e. where the condition (disease or stress state) influences the therapeutic response and side (adverse) effects from anti-inflammatory drugs. Mechanisms of drug-disease and drug disease interactions and the role of different stress states
-Rheumatology - particular emphasis on methods of measurement of clinical response effects of new agents, adverse effects from anti-rheumatic drugs
-Gastroenterology - with particular emphasis on animal and human models, mechanisms of mucosal inflammation and ulceration and effects of novel and established anti-ulcer, anti-inflammatory agents, or antiparasitic agents
-Neuro-Inflammation and Pain - model systems, pharmacology of new analgesic agents and mechanisms of neuro-inflammation and pain
-Novel drugs, natural products and nutraceuticals - and their effects on inflammatory processes, especially where there are indications of novel modes action compared with conventional drugs e.g. NSAIDs
-Muscle-immune interactions during inflammation [...]
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