Prevalence of Contact Allergy to Propolis—Testing With Different Propolis Patch Test Materials

IF 4.6 1区医学 Q2 ALLERGY

Contact Dermatitis Pub Date : 2025-03-02 DOI:10.1111/cod.14773

Annarita Antelmi, Ilaria Trave, Rosella Gallo, Emanuele Cozzani, Aurora Parodi, Magnus Bruze, Cecilia Svedman

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引用次数: 0

Abstract

Introduction

Propolis is a sticky substance produced by honeybees from plant resins collected from locally growing vegetation. Its chemical composition varies depending on the plant species visited by the bees. Contact dermatitis is commonly reported following exposure to cosmetics containing propolis or following the intake of food supplements.

Objectives

To investigate the prevalence of contact allergy to propolis in two dermatology clinics in Europe.

Methods

From February to July 2023, consecutive adult dermatitis patients were patch tested in the Department of Dermatology in Genova, Italy and in the Department of Occupational and Environmental Dermatology in Malmö, Sweden, with propolis (10% in petrolatum) originating from China. In Genova, propolis (10% in petrolatum) originating from Brazil was also tested.

Results

Out of 257 consecutive dermatitis patients patch tested in Genova, 16 (6.2%) reacted to propolis. Of these, 13 patients (5.1%) reacted to Brazilian propolis, one patient (0.4%) reacted to Chinese propolis, and two patients (0.8%) reacted to both. On patch testing 329 consecutive Swedish dermatitis patients with Chinese propolis, three patients (0.9%) reacted.

Conclusion

A significant difference was observed in the number of reactors to Brazilian propolis and Chinese propolis within the Italian group. When testing with Chinese propolis, a low prevalence of contact allergy was observed in both countries.

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蜂胶接触性过敏的流行——不同蜂胶贴片试验材料的试验。

简介：蜂胶是一种粘性物质，由蜜蜂从当地生长的植被中收集植物树脂制成。它的化学成分因蜜蜂所拜访的植物种类而异。接触性皮炎通常是在接触含有蜂胶的化妆品或摄入食品补充剂后报告的。目的：调查欧洲两个皮肤科诊所蜂胶接触性过敏的流行情况。方法：于2023年2月至7月在意大利热那亚皮肤科和瑞典Malmö职业与环境皮肤科对连续的成人皮炎患者进行了蜂胶（含凡士林10%）的贴片试验。在热那亚，还测试了产自巴西的蜂胶（含10%凡士林）。结果：热那亚257例皮炎患者中，16例（6.2%）对蜂胶有反应。其中13例（5.1%）患者对巴西蜂胶有反应，1例（0.4%）患者对中国蜂胶有反应，2例（0.8%）患者对两种蜂胶都有反应。在329例连续使用中国蜂胶的瑞典皮炎患者的斑贴试验中，3例患者（0.9%）有反应。结论：意大利群体对巴西蜂胶和中国蜂胶的反应器数量存在显著差异。当用中国蜂胶进行测试时，两国接触性过敏的患病率都很低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Contact Dermatitis 医学-过敏

CiteScore

4.60

自引率

30.90%

发文量

227

审稿时长

4-8 weeks

期刊介绍： Contact Dermatitis is designed primarily as a journal for clinicians who are interested in various aspects of environmental dermatitis. This includes both allergic and irritant (toxic) types of contact dermatitis, occupational (industrial) dermatitis and consumers" dermatitis from such products as cosmetics and toiletries. The journal aims at promoting and maintaining communication among dermatologists, industrial physicians, allergists and clinical immunologists, as well as chemists and research workers involved in industry and the production of consumer goods. Papers are invited on clinical observations, diagnosis and methods of investigation of patients, therapeutic measures, organisation and legislation relating to the control of occupational and consumers".