Opportunistic screening of osteoporosis using CT urography: comparison of diagnostic performance between contrast phases.

IF 1.1 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Youngjune Kim, Sejoon Lee, Eugene Lee, Joon Woo Lee
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引用次数: 0

Abstract

Background: Opportunistic screening of osteoporosis using computed tomography (CT) should be optimized according to CT protocols. However, to date, no study has evaluated the different contrast phases of CT urography in osteoporosis screening.

Purpose: To compare the diagnostic performance of different contrast phases of CT urography in opportunistic screening of osteoporosis.

Material and methods: In this single-center retrospective study, 210 consecutive patients (181 men, 29 women; mean age = 72.0 ± 9.5 years) who underwent both CT urography and dual-energy X-ray absorptiometry (DXA) within 3 months in July to December 2020 were included. The attenuation value was measured at the center of the L1 vertebral body in the axial plane of the precontrast, corticomedullary, and excretory phases. The mean and standard deviation (SD) of attenuation values were calculated. The area under the receiver operating characteristic curve (AUC) in differentiating osteoporosis versus osteopenia/normal was measured in each phase, and non-parametric comparisons between precontrast and the other phases were performed.

Results: According to DXA results, 90, 90, and 30 patients were classified into the normal, osteopenia, and osteoporosis groups, respectively. The mean ± SD of attenuation values in the precontrast, corticomedullary, and excretory phases were 114.9 ± 47.8, 132.8 ± 49.3, and 126.2 ± 47.2 HU, respectively. A significant difference was observed between AUCs measured in the precontrast (0.804, 95% confidence interval [CI] = 0.717-0.890) and corticomedullary phases (0.760, 95% CI = 0.661-0.860) (P = 0.003) and those between the precontrast and excretory phases (0.774, 95% CI = 0.678-0.869) (P = 0.005).

Conclusion: The precontrast phase outperformed the other phases in the opportunistic screening of osteoporosis using CT urography.

背景:使用计算机断层扫描(CT)进行骨质疏松症的机会性筛查应根据 CT 方案进行优化。目的:比较不同对比阶段的 CT 尿路造影在骨质疏松症机会性筛查中的诊断性能:在这项单中心回顾性研究中,纳入了在2020年7月至12月的3个月内同时接受CT尿路造影和双能X射线吸收测定(DXA)的210例连续患者(男性181例,女性29例;平均年龄=72.0 ± 9.5岁)。在对比前、皮质髓质期和排泄期的轴向平面上,以 L1 椎体为中心测量衰减值。计算衰减值的平均值和标准差(SD)。测量了每个阶段区分骨质疏松症和骨质疏松症/正常的接收器操作特征曲线下面积(AUC),并对对比前阶段和其他阶段进行了非参数比较:根据 DXA 结果,分别有 90、90 和 30 名患者被分为正常组、骨质疏松症组和骨质疏松症组。对比前、皮质髓质和排泄期衰减值的平均值(± SD)分别为 114.9 ± 47.8、132.8 ± 49.3 和 126.2 ± 47.2 HU。对比前阶段(0.804,95% 置信区间 [CI] = 0.717-0.890)和皮质髓质阶段(0.760,95% CI = 0.661-0.860)测得的 AUC 值(P = 0.003)与对比前阶段和排泄阶段(0.774,95% CI = 0.678-0.869)测得的 AUC 值(P = 0.005)之间存在明显差异:结论:在使用 CT 尿路造影对骨质疏松症进行机会性筛查时,对比前阶段优于其他阶段。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Acta radiologica
Acta radiologica 医学-核医学
CiteScore
2.70
自引率
0.00%
发文量
170
审稿时长
3-8 weeks
期刊介绍: Acta Radiologica publishes articles on all aspects of radiology, from clinical radiology to experimental work. It is known for articles based on experimental work and contrast media research, giving priority to scientific original papers. The distinguished international editorial board also invite review articles, short communications and technical and instrumental notes.
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