Magnetic resonance-guided focused ultrasound for uterine fibroids

IF 2.2 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Clinics Pub Date : 2025-01-01 DOI:10.1016/j.clinsp.2025.100603

Pedro Felipe Magalhães Peregrino, Marcos de Lorenzo Messina, José Maria Soares Júnior, Edmund Chada Baracat

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Abstract

Introduction

The uterine leiomyoma is a pelvic solid tumor more frequent in women. The Magnetic Resonance-Guided Focused Ultrasound (MRgFUS) is a technique aimed at diminishing hypermenorrhagia and dysmenorrhea in symptomatic women.

Objective

To show the effects subsequent to MRgFUS application on symptoms, quality of life, and myoma volume in symptomatic women.

Methods

Fifty-two patients with symptomatic uterine myomas underwent MRgFUS followed by clinical evaluation, pelvis MRI, and administration of the UFS-QoL questionnaire at 6 months and 12 months to detect symptom improvements and decrease in myoma volume.

Results

The mean myoma volume decreased 24 % after 6 months and 42 % after 12 months. The mean score on the UFS-QoL questionnaire increased 54 % after 6 months and 81 % after 12 months. There were no serious complications. Four patients had first-degree burns. No infection cases were reported. Two patients progressed to a myomectomy by surgical hysteroscopy and one of them underwent total hysterectomy 11 months after the MRgFUS treatment.

Conclusion

This case series suggests that MRgFUS therapy is viable and effective in reducing symptoms and improving the life quality of symptomatic patients.

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磁共振引导聚焦超声治疗子宫肌瘤

子宫平滑肌瘤是一种多发于女性的盆腔实体瘤。磁共振引导聚焦超声（MRgFUS）是一种旨在减少月经过多和痛经症状妇女的技术。目的探讨MRgFUS应用后对有症状女性肌瘤患者的症状、生活质量和肌瘤体积的影响。方法52例有症状的子宫肌瘤患者分别于6个月和12个月行MRgFUS、骨盆MRI和UFS-QoL问卷调查，观察症状改善和肌瘤体积减少情况。结果术后6个月肌瘤体积平均减少24%，术后12个月肌瘤体积平均减少42%。6个月后UFS-QoL问卷的平均得分增加了54%，12个月后增加了81%。没有严重的并发症。4名患者有一级烧伤。无感染病例报告。2例患者通过手术宫腔镜进行子宫肌瘤切除术，其中1例在MRgFUS治疗11个月后进行了全子宫切除术。结论本病例系列提示MRgFUS治疗在减轻症状和改善有症状患者生活质量方面是可行和有效的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinics 医学-医学：内科

CiteScore

4.10

自引率

3.70%

发文量

129

审稿时长

52 days

期刊介绍： CLINICS is an electronic journal that publishes peer-reviewed articles in continuous flow, of interest to clinicians and researchers in the medical sciences. CLINICS complies with the policies of funding agencies which request or require deposition of the published articles that they fund into publicly available databases. CLINICS supports the position of the International Committee of Medical Journal Editors (ICMJE) on trial registration.