Explanatory factors for the survival benefit among hip and knee arthroplasty patients with osteoarthritis

Jan M. Heijdra Suasnabar , Maaike Gademan , Liza van Steenbergen , Ewout Steyerberg , Rob Nelissen , Wilbert van den Hout
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Abstract

Objective

Studies have shown that osteoarthritis patients who underwent a primary total hip or knee arthroplasty (THA/TKA) experience better survival than the general population, yet there is limited evidence explaining this counter-intuitive difference. We investigated whether this better survival is also present in the Netherlands and to what extent it could be explained by a patient selection effect, whereby patients with more favorable health and socioeconomic status (SES) are more likely to receive THA/TKA.

Design

In this registry-based study, we compared the survival, health and SES of THA/TKA osteoarthritis patients to those of the general Dutch population. The patient cohort included 224,785 THA and 198,691 TKA patients who underwent an arthroplasty between 2010–2020. The proportions of the survival differences explained by better health (as measured by the EQ-5D) and SES (postcode-level) were estimated using spline-based survival models and Dutch lifetables.

Results

The eleven-year survival of THA and TKA patients were 8.7% and 8.1% better than the general population. Although health and SES predicted individual survival, they explained only ≈7% of the survival benefit.

Conclusions

Our study confirmed that Dutch osteoarthritis THA/TKA patients experience better survival than the general population, but raises important questions as to the explanation. A more favorable health status and/or SES did not explain most of the survival benefit. This may be partly due to limitations of the available measures of health and SES in our study, but also leaves other explanations (e.g. barriers to receive access to care, lifestyle changes) open for further research.
骨关节炎髋关节和膝关节置换术患者生存获益的解释因素
研究表明,接受原发性全髋关节或膝关节置换术(THA/TKA)的骨关节炎患者比一般人群生存率更高,但解释这种反直觉差异的证据有限。我们调查了荷兰是否也存在这种更好的生存率,以及在多大程度上可以用患者选择效应来解释,即健康状况和社会经济地位(SES)更有利的患者更有可能接受THA/TKA。设计:在这项基于登记的研究中,我们比较了THA/TKA骨关节炎患者与荷兰普通人群的生存、健康和SES。患者队列包括224,785例THA和198,691例TKA患者,他们在2010-2020年间接受了关节置换术。使用基于样条的生存模型和荷兰生命表来估计,较好的健康状况(由EQ-5D测量)和SES(邮政编码水平)解释的生存差异的比例。结果THA和TKA患者11年生存率分别比普通人群高8.7%和8.1%。虽然健康和社会地位可以预测个体的生存,但它们只能解释约7%的生存效益。结论一项研究证实,荷兰骨关节炎THA/TKA患者的生存率高于一般人群,但对其解释提出了重要问题。更有利的健康状况和/或社会经济地位并不能解释大部分的生存优势。这可能部分是由于我们研究中可用的健康和社会经济地位测量方法的局限性,但也为进一步研究留下了其他解释(例如获得护理的障碍,生活方式的改变)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Osteoarthritis and cartilage open
Osteoarthritis and cartilage open Orthopedics, Sports Medicine and Rehabilitation
CiteScore
3.30
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