Graphene–Multiwalled Carbon Nanotubes Modified Glassy Carbon Electrodes for Simultaneous Detection of Ascorbic Acid, Dopamine, and Uric Acid

IF 3.7 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

ACS Omega Pub Date : 2025-02-20 DOI:10.1021/acsomega.4c0964610.1021/acsomega.4c09646

Hsien-Hsu Hsieh, Jie-Yu Xu, Jing-Tong Lin, Yun-Ting Chiang and Yu-Ching Weng*,

{"title":"Graphene–Multiwalled Carbon Nanotubes Modified Glassy Carbon Electrodes for Simultaneous Detection of Ascorbic Acid, Dopamine, and Uric Acid","authors":"Hsien-Hsu Hsieh, Jie-Yu Xu, Jing-Tong Lin, Yun-Ting Chiang and Yu-Ching Weng*, ","doi":"10.1021/acsomega.4c0964610.1021/acsomega.4c09646","DOIUrl":null,"url":null,"abstract":"<p >This study compares the sensing performance of glassy carbon electrodes (GCE) modified with graphene (GR), multiwalled carbon nanotubes (MWCNTs), and graphene–multiwalled carbon nanotube (GR-MWCNT) composites for the simultaneous detection of ascorbic acid (AA), dopamine (DA), and uric acid (UA). Among these electrodes, GR-MWCNT/GCE exhibited the highest sensitivity and the lowest detection limit. Using differential pulse voltammetry (DPV), AA, DA, and UA can be simultaneously detected at low potentials of −0.032, 0.206, and 0.34 V vs Ag/AgCl, with sensitivities of 0.076, 1.38, and 0.181 μA μM<sup>–1</sup> and detection limits (LOD) of 6.71, 0.58, and 7.30 μM, respectively. The GR-MWCNT/GCE also demonstrated good stability, reproducibility, and excellent anti-interference capability. This newly fabricated sensor was confirmed to be applicable for the simultaneous detection of AA, DA, and UA in real serum and urine samples.</p>","PeriodicalId":22,"journal":{"name":"ACS Omega","volume":"10 8","pages":"8160–8171 8160–8171"},"PeriodicalIF":3.7000,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsomega.4c09646","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Omega","FirstCategoryId":"92","ListUrlMain":"https://pubs.acs.org/doi/10.1021/acsomega.4c09646","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

This study compares the sensing performance of glassy carbon electrodes (GCE) modified with graphene (GR), multiwalled carbon nanotubes (MWCNTs), and graphene–multiwalled carbon nanotube (GR-MWCNT) composites for the simultaneous detection of ascorbic acid (AA), dopamine (DA), and uric acid (UA). Among these electrodes, GR-MWCNT/GCE exhibited the highest sensitivity and the lowest detection limit. Using differential pulse voltammetry (DPV), AA, DA, and UA can be simultaneously detected at low potentials of −0.032, 0.206, and 0.34 V vs Ag/AgCl, with sensitivities of 0.076, 1.38, and 0.181 μA μM^–1 and detection limits (LOD) of 6.71, 0.58, and 7.30 μM, respectively. The GR-MWCNT/GCE also demonstrated good stability, reproducibility, and excellent anti-interference capability. This newly fabricated sensor was confirmed to be applicable for the simultaneous detection of AA, DA, and UA in real serum and urine samples.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

ACS Omega Chemical Engineering-General Chemical Engineering

CiteScore

6.60

自引率

4.90%

发文量

3945

审稿时长

2.4 months

期刊介绍： ACS Omega is an open-access global publication for scientific articles that describe new findings in chemistry and interfacing areas of science, without any perceived evaluation of immediate impact.