Posterior scalp block with bupivacaine and dexmedetomidine for pain management in posterior fossa surgeries: a prospective, double blind randomized controlled trial.

IF 1.4 Q4 CLINICAL NEUROLOGY

Pain management Pub Date : 2025-03-01 DOI:10.1080/17581869.2025.2470607

Sheethal N, Ashwin Pai V, Ramya Kateel, Arjun Balakrishnan, Raghavendra Nayak, Girish R Menon, Sunitha M, Ravitej Bhat

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引用次数: 0

Abstract

Background: Pain management in posterior fossa surgeries poses significant challenges, with opioid-based approaches causing unwanted side effects. This study evaluates the efficacy of posterior scalp block using bupivacaine and dexmedetomidine compared to skin infiltration for managing perioperative pain.

Methods: In this prospective, double-blind, randomized controlled trial, 34 adult patients undergoing elective posterior fossa surgeries were equally assigned to either posterior scalp block or skin infiltration groups. Outcomes measured included hemodynamic parameters, pain scores, opioid consumption, time to first analgesic, and sedation levels.

Results: The posterior scalp block group showed significantly lower opioid consumption (211.47 ± 101.95 mcg vs 305.88 ± 117.10 mcg; p < 0.01) and pain scores (VAS 2.29 ± 0.9 vs 5.06 ± 1.3; p < 0.001) at 24 hours post-surgery. This group also demonstrated better hemodynamic stability and fewer rescue opioid requirements (9 vs 15 patients; p < 0.009).

Conclusions: Posterior scalp block with bupivacaine and dexmedetomidine significantly improves pain management, reduces opioid use, and provides better hemodynamic stability compared to skin infiltration in posterior fossa surgeries.

Clinical trial registration: CTRI/2023/07/0554959.

查看原文本刊更多论文

布比卡因和右美托咪定后头皮阻滞治疗后颅窝手术疼痛：一项前瞻性、双盲、随机对照试验。

背景：后窝手术中的疼痛管理是一项重大挑战，以阿片类药物为基础的方法会导致不必要的副作用。本研究评估了使用布比卡因和右美托咪定进行后头皮阻滞与皮肤浸润治疗围手术期疼痛的疗效：在这项前瞻性、双盲、随机对照试验中，34 名接受后窝择期手术的成年患者被平均分配到后头皮阻滞组或皮肤浸润组。测量结果包括血液动力学参数、疼痛评分、阿片类药物消耗量、首次镇痛时间和镇静水平：与后窝手术中的皮肤浸润相比，布比卡因和右美托咪定的头皮后阻滞能明显改善疼痛管理，减少阿片类药物的使用，并提供更好的血流动力学稳定性：CTRI/2023/07/0554959.

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pain management CLINICAL NEUROLOGY-

CiteScore

2.90

自引率

5.90%

发文量