Yasemin Çakır Kıymaz , Sümeyye Kara Yeşildağ , Sevgi Baltacı , Ayşenur Çömez Baysal , Cihad Baysal , Ertuğrul Keskin , Suna Bozkurt , Mürşit Hasbek , Seyit Ali Büyüktuna , Nazif Elaldı
{"title":"Spontaneous bacterial peritonitis due to Brucella in an HBV-positive cirrhotic patient","authors":"Yasemin Çakır Kıymaz , Sümeyye Kara Yeşildağ , Sevgi Baltacı , Ayşenur Çömez Baysal , Cihad Baysal , Ertuğrul Keskin , Suna Bozkurt , Mürşit Hasbek , Seyit Ali Büyüktuna , Nazif Elaldı","doi":"10.1016/j.jiac.2025.102663","DOIUrl":null,"url":null,"abstract":"<div><div>Spontaneous bacterial peritonitis (SBP) is a severe complication of cirrhosis, occurring in approximately 15 % of cirrhotic patients. The most common causative pathogens of SBP are <em>Escherichia coli</em> and <em>Klebsiella pneumoniae</em>. Although brucellosis can cause various complications, it is a rare cause of peritonitis. Herein, we report a case of a 30-year-old male with chronic hepatitis B who presented with fever, night sweats, weight loss, abdominal pain, and distension. <em>Brucella</em> spp. was isolated from blood and peritoneal fluid cultures. The patient fully recovered following six weeks of treatment with oral doxycycline (100 mg twice daily) and rifampicin (600 mg/day). No relapses or complications were observed during follow-up.</div></div>","PeriodicalId":16103,"journal":{"name":"Journal of Infection and Chemotherapy","volume":"31 4","pages":"Article 102663"},"PeriodicalIF":1.9000,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Infection and Chemotherapy","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1341321X25000601","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
Abstract
Spontaneous bacterial peritonitis (SBP) is a severe complication of cirrhosis, occurring in approximately 15 % of cirrhotic patients. The most common causative pathogens of SBP are Escherichia coli and Klebsiella pneumoniae. Although brucellosis can cause various complications, it is a rare cause of peritonitis. Herein, we report a case of a 30-year-old male with chronic hepatitis B who presented with fever, night sweats, weight loss, abdominal pain, and distension. Brucella spp. was isolated from blood and peritoneal fluid cultures. The patient fully recovered following six weeks of treatment with oral doxycycline (100 mg twice daily) and rifampicin (600 mg/day). No relapses or complications were observed during follow-up.
期刊介绍:
The Journal of Infection and Chemotherapy (JIC) — official journal of the Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases — welcomes original papers, laboratory or clinical, as well as case reports, notes, committee reports, surveillance and guidelines from all parts of the world on all aspects of chemotherapy, covering the pathogenesis, diagnosis, treatment, and control of infection, including treatment with anticancer drugs. Experimental studies on animal models and pharmacokinetics, and reports on epidemiology and clinical trials are particularly welcome.