Abnormal resting-state brain networks and their relationship with cognitive reappraisal preferences in depressive tendencies

IF 2.7 4区医学 Q3 NEUROSCIENCES

Brain Research Pub Date : 2025-02-26 DOI:10.1016/j.brainres.2025.149522

Yan Sun, Xinge Mao, Peiyu Hou

{"title":"Abnormal resting-state brain networks and their relationship with cognitive reappraisal preferences in depressive tendencies","authors":"Yan Sun, Xinge Mao, Peiyu Hou","doi":"10.1016/j.brainres.2025.149522","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>Currently, the neural mechanisms underlying the topological changes in the brains of individuals with depressive tendencies and the decline in their emotion regulation abilities remain largely unknown. Therefore, this study investigates resting-state brain network characteristics in college students with depressive tendencies (DT) and their preference to cognitive reappraisal strategies.</div></div><div><h3>Method</h3><div>A group of 38 DT students and 41 healthy controls (HCs) were assessed using questionnaires on cognitive reappraisal sub-strategies, followed by alpha and beta frequency band EEG feature extraction.</div></div><div><h3>Results</h3><div>Through complex network analysis, DT participants showed significantly reduced preferences for positive reappraisal and detached reappraisal compared to HCs, while exhibiting higher preferences for involved reappraisal and negative reappraisal. Additionally, abnormalities in brain network centrality were observed, particularly in the frontal and limbic lobes across various frequency bands. A significant correlation was found between the preference for cognitive reappraisal sub-strategies in DT participants and significant changes in graph indices.</div></div><div><h3>Conclusions</h3><div>The findings highlight substantial alterations in the resting-state brain networks of DT individuals, closely associated with cognitive reappraisal strategy preferences. These alterations may affect emotion regulation strategy choices, offering insights into the neural mechanisms of emotional regulation difficulties in DT.</div></div>","PeriodicalId":9083,"journal":{"name":"Brain Research","volume":"1854 ","pages":"Article 149522"},"PeriodicalIF":2.7000,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brain Research","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0006899325000800","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NEUROSCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

Objective

Currently, the neural mechanisms underlying the topological changes in the brains of individuals with depressive tendencies and the decline in their emotion regulation abilities remain largely unknown. Therefore, this study investigates resting-state brain network characteristics in college students with depressive tendencies (DT) and their preference to cognitive reappraisal strategies.

Method

A group of 38 DT students and 41 healthy controls (HCs) were assessed using questionnaires on cognitive reappraisal sub-strategies, followed by alpha and beta frequency band EEG feature extraction.

Results

Through complex network analysis, DT participants showed significantly reduced preferences for positive reappraisal and detached reappraisal compared to HCs, while exhibiting higher preferences for involved reappraisal and negative reappraisal. Additionally, abnormalities in brain network centrality were observed, particularly in the frontal and limbic lobes across various frequency bands. A significant correlation was found between the preference for cognitive reappraisal sub-strategies in DT participants and significant changes in graph indices.

Conclusions

The findings highlight substantial alterations in the resting-state brain networks of DT individuals, closely associated with cognitive reappraisal strategy preferences. These alterations may affect emotion regulation strategy choices, offering insights into the neural mechanisms of emotional regulation difficulties in DT.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Brain Research 医学-神经科学

CiteScore

5.90

自引率

3.40%

发文量

268

审稿时长

47 days

期刊介绍： An international multidisciplinary journal devoted to fundamental research in the brain sciences. Brain Research publishes papers reporting interdisciplinary investigations of nervous system structure and function that are of general interest to the international community of neuroscientists. As is evident from the journals name, its scope is broad, ranging from cellular and molecular studies through systems neuroscience, cognition and disease. Invited reviews are also published; suggestions for and inquiries about potential reviews are welcomed. With the appearance of the final issue of the 2011 subscription, Vol. 67/1-2 (24 June 2011), Brain Research Reviews has ceased publication as a distinct journal separate from Brain Research. Review articles accepted for Brain Research are now published in that journal.