Abnormal resting-state brain networks and their relationship with cognitive reappraisal preferences in depressive tendencies

IF 2.6 4区医学 Q3 NEUROSCIENCES

Brain Research Pub Date : 2025-02-26 DOI:10.1016/j.brainres.2025.149522

Yan Sun, Xinge Mao, Peiyu Hou

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引用次数: 0

Abstract

Objective

Currently, the neural mechanisms underlying the topological changes in the brains of individuals with depressive tendencies and the decline in their emotion regulation abilities remain largely unknown. Therefore, this study investigates resting-state brain network characteristics in college students with depressive tendencies (DT) and their preference to cognitive reappraisal strategies.

Method

A group of 38 DT students and 41 healthy controls (HCs) were assessed using questionnaires on cognitive reappraisal sub-strategies, followed by alpha and beta frequency band EEG feature extraction.

Results

Through complex network analysis, DT participants showed significantly reduced preferences for positive reappraisal and detached reappraisal compared to HCs, while exhibiting higher preferences for involved reappraisal and negative reappraisal. Additionally, abnormalities in brain network centrality were observed, particularly in the frontal and limbic lobes across various frequency bands. A significant correlation was found between the preference for cognitive reappraisal sub-strategies in DT participants and significant changes in graph indices.

Conclusions

The findings highlight substantial alterations in the resting-state brain networks of DT individuals, closely associated with cognitive reappraisal strategy preferences. These alterations may affect emotion regulation strategy choices, offering insights into the neural mechanisms of emotional regulation difficulties in DT.

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抑郁倾向大学生静息状态脑网络异常及其与认知重评价偏好的关系。

目的：目前，抑郁症患者大脑拓扑结构变化和情绪调节能力下降的神经机制尚不清楚。因此，本研究旨在探讨抑郁倾向大学生的静息状态脑网络特征及其对认知重评价策略的偏好。方法：采用认知重评子策略问卷对38名DT学生和41名健康对照进行评估，并进行α和β频带EEG特征提取。结果：通过复杂网络分析，DT参与者对积极重评和超然重评的偏好显著低于hc参与者，而对涉入重评和消极重评的偏好较高。此外，在不同频段的大脑网络中心性异常被观察到，特别是在额叶和边缘叶。认知重评子策略的偏好与图表指数的显著变化之间存在显著的相关性。结论：研究结果强调了DT个体静息状态脑网络的实质性改变，与认知重评价策略偏好密切相关。这些变化可能会影响情绪调节策略的选择，为研究DT患者情绪调节困难的神经机制提供了新的思路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Brain Research 医学-神经科学

CiteScore

5.90

自引率

3.40%

发文量

268

审稿时长

47 days

期刊介绍： An international multidisciplinary journal devoted to fundamental research in the brain sciences. Brain Research publishes papers reporting interdisciplinary investigations of nervous system structure and function that are of general interest to the international community of neuroscientists. As is evident from the journals name, its scope is broad, ranging from cellular and molecular studies through systems neuroscience, cognition and disease. Invited reviews are also published; suggestions for and inquiries about potential reviews are welcomed. With the appearance of the final issue of the 2011 subscription, Vol. 67/1-2 (24 June 2011), Brain Research Reviews has ceased publication as a distinct journal separate from Brain Research. Review articles accepted for Brain Research are now published in that journal.