Linking Metastatic Potential and Viscoelastic Properties of Breast Cancer Spheroids via Dynamic Compression and Relaxation in Microfluidics (Adv. Healthcare Mater. 6/2025)

IF 10 2区医学 Q1 ENGINEERING, BIOMEDICAL

Advanced Healthcare Materials Pub Date : 2025-03-03 DOI:10.1002/adhm.202570036

Margherita Tavasso, Ankur D. Bordoloi, Elsa Tanré, Sanne A. H. Dekker, Valeria Garbin, Pouyan E. Boukany

引用次数: 0

Abstract

Viscoelastic Properties of Breast Cancer Spheroids

In article 2402715, Ankur D. Bordoloi, Pouyan E. Boukany, and co-workers link the viscoelastic properties of breast cancer spheroids to their metastatic potential. In a constricted microfluidic device, benign spheroids are found to be more elastic and viscous than malignant ones, with differences in their relaxation times, morphology, and cytoskeletal organization.

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来源期刊

Advanced Healthcare Materials 工程技术-生物材料

CiteScore

14.40

自引率

3.00%

发文量

600

审稿时长

1.8 months

期刊介绍： Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.