NiCu-layered double hydroxide–modified CuO nanorods for enhanced non-enzymatic glucose sensing

IF 5.3 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchimica Acta Pub Date : 2025-03-01 DOI:10.1007/s00604-025-07061-9

Jiahao Yang, Lan Xu

{"title":"NiCu-layered double hydroxide–modified CuO nanorods for enhanced non-enzymatic glucose sensing","authors":"Jiahao Yang, Lan Xu","doi":"10.1007/s00604-025-07061-9","DOIUrl":null,"url":null,"abstract":"<div><p>A flexible non-enzymatic glucose sensor with high sensitivity (NiCu-LDH/CuO/NCC) was prepared by growing NiCu-layered double hydroxide (NiCu-LDH)–modified CuO nanorods on N-doped carbon cloth (NCC) using hydrothermal method and electrodeposition. The NCC provided abundant attachment sites and good electrical conductivity for CuO nanorods, and the hierarchical nanostructures (NiCu-LDH/CuO) had large specific surface area and highly catalytic active sites, which facilitated the electrooxidation of glucose. The effect of the ratio of Ni to Cu on the electrocatalytic performance of NiCu-LDH/CuO/NCC was evaluated. The results indicated that the optimized NiCu-LDH/CuO/NCC (Ni/Cu molar ratio of 2:1) had good electrocatalytic oxidation toward glucose, and exhibited high sensitivity (11.545 mA cm<sup>−2</sup> mM<sup>−1</sup>), low detection limit (0.26 μM), large linear range (0.001–1.5 mM), and good stability (95% after 28 days). Therefore, the hierarchical nanostructure is suitable for the construction of flexible non-enzymatic glucose sensors with high sensitivity, indicating that the combination of transition metal oxides and LDH provides a unique opportunity for designing high-performance electrochemical non-enzymatic glucose sensors.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 3","pages":""},"PeriodicalIF":5.3000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microchimica Acta","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s00604-025-07061-9","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}

引用次数: 0

Abstract

A flexible non-enzymatic glucose sensor with high sensitivity (NiCu-LDH/CuO/NCC) was prepared by growing NiCu-layered double hydroxide (NiCu-LDH)–modified CuO nanorods on N-doped carbon cloth (NCC) using hydrothermal method and electrodeposition. The NCC provided abundant attachment sites and good electrical conductivity for CuO nanorods, and the hierarchical nanostructures (NiCu-LDH/CuO) had large specific surface area and highly catalytic active sites, which facilitated the electrooxidation of glucose. The effect of the ratio of Ni to Cu on the electrocatalytic performance of NiCu-LDH/CuO/NCC was evaluated. The results indicated that the optimized NiCu-LDH/CuO/NCC (Ni/Cu molar ratio of 2:1) had good electrocatalytic oxidation toward glucose, and exhibited high sensitivity (11.545 mA cm⁻² mM⁻¹), low detection limit (0.26 μM), large linear range (0.001–1.5 mM), and good stability (95% after 28 days). Therefore, the hierarchical nanostructure is suitable for the construction of flexible non-enzymatic glucose sensors with high sensitivity, indicating that the combination of transition metal oxides and LDH provides a unique opportunity for designing high-performance electrochemical non-enzymatic glucose sensors.

Graphical Abstract

查看原文本刊更多论文

nicu层状双氢氧化物修饰氧化铜纳米棒增强非酶葡萄糖传感

采用水热法和电沉积法在n掺杂碳布（NCC）上生长nicu -层状双氢氧化物（NiCu-LDH）修饰的CuO纳米棒，制备了一种高灵敏度柔性无酶葡萄糖传感器NiCu-LDH/CuO/NCC。NCC为CuO纳米棒提供了丰富的附着位点和良好的导电性，并且分层纳米结构（NiCu-LDH/CuO）具有较大的比表面积和高的催化活性位点，有利于葡萄糖的电氧化。考察了镍铜比对NiCu-LDH/CuO/NCC电催化性能的影响。结果表明，优化后的NiCu-LDH/CuO/NCC （Ni/Cu摩尔比为2:1）对葡萄糖具有良好的电催化氧化性能，灵敏度高（11.545 mA cm−2 mM−1），检出限低（0.26 μM），线性范围大（0.001 ~ 1.5 mM），稳定性好（28 d后95%）。因此，层次化的纳米结构适合于构建高灵敏度的柔性非酶葡萄糖传感器，这表明过渡金属氧化物与LDH的结合为设计高性能的电化学非酶葡萄糖传感器提供了独特的机会。图形抽象

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Microchimica Acta 化学-分析化学

CiteScore

9.80

自引率

5.30%

发文量

410

审稿时长

2.7 months

期刊介绍： As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.