Disfunción endotelial y anomalías vasculares en acromegalia. A propósito de un caso

IF 0.7 4区医学 Q4 NEUROSCIENCES

Neurocirugia Pub Date : 2025-03-01 DOI:10.1016/j.neucir.2024.09.006

Ana Irigaray Echarri , M. Dolores Ollero García-Agulló , José Jorge Ortez Toro , Idoya Zazpe Cenoz

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引用次数: 0

Abstract

In patients with acromegaly, the pleiotropic effects of GH and IGF-1 have been associated with the development of endothelial dysfunction and vascular abnormalities.

We present the case of a 45-year-old male diagnosed with acromegaly. Magnetic resonance imaging identified a marked dilatation and medialization of both cavernous internal carotid arteries (ICA), leading to a narrow intercarotid distance, a phenomenon known as “carotid kisses”.

This vascular alteration has been described in greater proportion in patients with acromegaly. The anomalies that are also present with greater prevalence in these patients are: aneurysms of the ICA, protrusion of the ICA into the sphenoid sinus, narrow intercarotid distance, fusiform dilatation of the ICA and dehiscence of this artery in the bony canal. The presence of such alterations increases the risk of injury to the ICA.

Pre-surgical detection of such abnormalities is essential to ensure the safety of the surgical approach.

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肢端肥大症的内皮功能障碍和血管异常。病例报告

在肢端肥大症患者中，生长激素和IGF-1的多效性作用与内皮功能障碍和血管异常的发展有关。我们提出的情况下，45岁的男性诊断为肢端肥大症。磁共振成像发现两个海绵状颈内动脉（ICA）明显扩张和中间化，导致颈动脉间距狭窄，这种现象被称为“颈动脉之吻”。这种血管改变在肢端肥大症患者中所占比例更大。在这些患者中更常见的异常还有：颈内动脉动脉瘤、颈内动脉向蝶窦内突出、颈动脉间距狭窄、颈内动脉梭状扩张和骨管内动脉破裂。这种改变的存在增加了ICA损伤的风险。术前检测此类异常对于确保手术入路的安全性至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurocirugia 医学-神经科学

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

60 days

期刊介绍： Neurocirugía is the official Journal of the Spanish Society of Neurosurgery (SENEC). It is published every 2 months (6 issues per year). Neurocirugía will consider for publication, original clinical and experimental scientific works associated with neurosurgery and other related neurological sciences. All manuscripts are submitted for review by experts in the field (peer review) and are carried out anonymously (double blind). The Journal accepts works written in Spanish or English.