Durational effect of ambient air pollution on hospital admissions of schizophrenia: a time series analysis.

IF 3.6 2区医学 Q1 PSYCHIATRY

Social Psychiatry and Psychiatric Epidemiology Pub Date : 2025-02-28 DOI:10.1007/s00127-025-02831-5

Xiaolan Huang, Chun Zhou, Xianyan Tang, Yuhua Wei, Dongmei Li, Bing Shen, Qinggui Lei, Qian Zhou, Jun Lan, Yanli Qin, Li Su, Jianxiong Long

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引用次数: 0

Abstract

Background: Schizophrenia may be exacerbated by ambient air pollution. In this study, we aim to explore the association of air pollution with hospital admission for schizophrenia in Liuzhou, China.

Methods: The daily concentration of air pollutants was gathered from an average of seven fixed monitoring sites in Liuzhou, while the daily admission data for schizophrenia was received from The Guangxi Zhuang Autonomous Region Brain Hospital. A Poisson generalized linear regression model in conjunction with a distributed lag nonlinear model was utilized to quantify the exposure-lag-response connection between ambient air pollution and schizophrenia hospitalization. The stratification analysis was then carried out by age, gender, and season.

Results: PM_2.5, PM₁₀, and SO₂ was significantly associated with elevated number of schizophrenia hospitalization. We observed the largest single-day effects of PM_2.5 at lag 17 day, PM₁₀ at lag 17 day, and SO₂ at lag 28 day, with the corresponding RRs being 1.01611 (95% CI:1.00652-1.02579), 1.01648 (95% CI:1.00603-1.02704), and 1.02001 (95% CI: 1.00001-1.04041), respectively. Stratification analysis revealed that patients who were < 45 years old and female were more vulnerable to hospitalization due to exposure to PM_2.5 and PM₁₀. The effects of PM_2.5 and PM₁₀ were more noticeable during the cooler seasons than during the warmer one.

Conclusions: This study reveals that being exposed to PM_2.5, PM₁₀, and SO₂ may increase the chance of schizophrenia hospitalization.

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来源期刊

Social Psychiatry and Psychiatric Epidemiology 医学-精神病学

CiteScore

8.50

自引率

2.30%

发文量

184

审稿时长

3-6 weeks

期刊介绍： Social Psychiatry and Psychiatric Epidemiology is intended to provide a medium for the prompt publication of scientific contributions concerned with all aspects of the epidemiology of psychiatric disorders - social, biological and genetic. In addition, the journal has a particular focus on the effects of social conditions upon behaviour and the relationship between psychiatric disorders and the social environment. Contributions may be of a clinical nature provided they relate to social issues, or they may deal with specialised investigations in the fields of social psychology, sociology, anthropology, epidemiology, health service research, health economies or public mental health. We will publish papers on cross-cultural and trans-cultural themes. We do not publish case studies or small case series. While we will publish studies of reliability and validity of new instruments of interest to our readership, we will not publish articles reporting on the performance of established instruments in translation. Both original work and review articles may be submitted.