Interim Estimates of 2024-2025 COVID-19 Vaccine Effectiveness Among Adults Aged ≥18 Years - VISION and IVY Networks, September 2024-January 2025.

IF 25.4 1区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

MMWR. Morbidity and mortality weekly report Pub Date : 2025-02-27 DOI:10.15585/mmwr.mm7406a1

Ruth Link-Gelles, Sean Chickery, Alexander Webber, Toan C Ong, Elizabeth A K Rowley, Malini B DeSilva, Kristin Dascomb, Stephanie A Irving, Nicola P Klein, Shaun J Grannis, Michelle A Barron, Sarah E Reese, Charlene McEvoy, Tamara Sheffield, Allison L Naleway, Ousseny Zerbo, Colin Rogerson, Wesley H Self, Yuwei Zhu, Adam S Lauring, Emily T Martin, Ithan D Peltan, Adit A Ginde, Nicholas M Mohr, Kevin W Gibbs, David N Hager, Matthew E Prekker, Amira Mohamed, Nicholas Johnson, Jay S Steingrub, Akram Khan, Jamie R Felzer, Abhijit Duggal, Jennifer G Wilson, Nida Qadir, Christopher Mallow, Jennie H Kwon, Cristie Columbus, Ivana A Vaughn, Basmah Safdar, Jarrod M Mosier, Estelle S Harris, James D Chappell, Natasha Halasa, Cassandra Johnson, Karthik Natarajan, Nathaniel M Lewis, Sascha Ellington, Emily L Reeves, Jennifer DeCuir, Meredith McMorrow, Clinton R Paden, Amanda B Payne, Fatimah S Dawood, Diya Surie

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引用次数: 0

Abstract

COVID-19 vaccination averted approximately 68,000 hospitalizations during the 2023-24 respiratory season. In June 2024, CDC and the Advisory Committee on Immunization Practices (ACIP) recommended that all persons aged ≥6 months receive a 2024-2025 COVID-19 vaccine, which targets Omicron JN.1 and JN.1-derived sublineages. Interim effectiveness of 2024-2025 COVID-19 vaccines was estimated against COVID-19-associated emergency department (ED) or urgent care (UC) visits during September 2024-January 2025 among adults aged ≥18 years in one CDC-funded vaccine effectiveness (VE) network, against COVID-19-associated hospitalization in immunocompetent adults aged ≥65 years in two networks, and against COVID-19-associated hospitalization among adults aged ≥65 years with immunocompromising conditions in one network. Among adults aged ≥18 years, VE against COVID-19-associated ED/UC visits was 33% (95% CI = 28%-38%) during the first 7-119 days after vaccination. Among immunocompetent adults aged ≥65 years from two CDC networks, VE estimates against COVID-19-associated hospitalization were 45% (95% CI = 36%-53%) and 46% (95% CI = 26%-60%) during the first 7-119 days after vaccination. Among adults aged ≥65 years with immunocompromising conditions in one network, VE was 40% (95% CI = 21%-54%) during the first 7-119 days after vaccination. These findings demonstrate that vaccination with a 2024-2025 COVID-19 vaccine dose provides additional protection against COVID-19-associated ED/UC encounters and hospitalizations compared with not receiving a 2024-2025 dose and support current CDC and ACIP recommendations that all persons aged ≥6 months receive a 2024-2025 COVID-19 vaccine dose.

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来源期刊

MMWR. Morbidity and mortality weekly report PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -

CiteScore

65.40

自引率

0.90%

发文量

309

期刊介绍： The Morbidity and Mortality Weekly Report (MMWR ) series is prepared by the Centers for Disease Control and Prevention (CDC). Often called “the voice of CDC,” the MMWR series is the agency’s primary vehicle for scientific publication of timely, reliable, authoritative, accurate, objective, and useful public health information and recommendations. MMWR readership predominantly consists of physicians, nurses, public health practitioners, epidemiologists and other scientists, researchers, educators, and laboratorians.