29. Early growth in first trimester scan in adolescent pregnancies: Results from a comparative cohort study.

IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY
Anastasia Vatopoulou , Athina Samara , Hara Skentou , Katerina Dadouli , Fani Gkrozou , Antonios Garas , Sotirios Sotiriou
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引用次数: 0

Abstract

Background

In the present study we aim to assess the Crown-rump length (CRL) values measured in first trimester scan in adolescent pregnancies compared with the respective CRL values in adult pregnancies.

Methods

All consecutive pregnancies that underwent a first trimester ultrasound scan in two fetomaternal units in Greece during a twelve-year period were included in the present study. Ultrasound findings, demographic characteristics and medical records were retrospectively reviewed and recorded in an anonymous database. Cases with a maternal age< 20 years were characterized as adolescent pregnancies, and all other cases were grouped as adult pregnancies (control group). All statistical analyses were performed using R (version 4.2.2) software packages. The Kolmogorov-Smirnov test was used to test the normality of the variables. Multivariate linear regression model and linear regression model were used to assess the association between the weighted for gestational age CRL and the independent variables. The results are represented as the effect size of the CRL. Statistical significance was set at P< 0.05 (two tailed).

Results

In total, 3234 pregnancies were included in the present study; 325 were identified as adolescent pregnancies and 2909 were adult pregnancies. In multivariate analysis, CRL values were statistically significant lower (52.6 mm and 58.8 mm respectively) in adolescent pregnancies (p< 0.001).

Conclusions

Based on our results, pregnancy in adolescents has been associated, with statistically significant lower CRL measures compared with adult pregnancies. More prospective studies with larger cohort series are needed.
29. 在青春期怀孕的早期妊娠扫描早期生长:来自一项比较队列研究的结果。
在本研究中,我们的目的是评估冠臀长(CRL)值测量在青春期怀孕的前三个月扫描与成年怀孕各自的CRL值进行比较。方法:本研究纳入了希腊12年期间在两个妇产科进行妊娠早期超声扫描的所有连续妊娠。对超声检查结果、人口统计学特征和医疗记录进行回顾性审查,并记录在匿名数据库中。产妇年龄较大的病例;其中20年为青少年怀孕,其余均为成人怀孕(对照组)。所有统计分析均使用R(4.2.2版)软件包进行。使用Kolmogorov-Smirnov检验来检验变量的正态性。采用多元线性回归模型和线性回归模型评估胎龄CRL加权值与自变量的相关性。结果表示为CRL的效应大小。统计学意义设为P<;0.05(双尾)。结果本研究共纳入3234例妊娠;325例为青少年怀孕,2909例为成人怀孕。在多变量分析中,青少年怀孕的CRL值显著降低(分别为52.6 mm和58.8 mm) (p<;0.001)。结论:根据我们的研究结果,青少年怀孕与成人怀孕相关,与成人怀孕相比,CRL测量值有统计学意义上的显著降低。需要更多的前瞻性研究和更大的队列研究。
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来源期刊
CiteScore
3.90
自引率
11.10%
发文量
251
审稿时长
57 days
期刊介绍: Journal of Pediatric and Adolescent Gynecology includes all aspects of clinical and basic science research in pediatric and adolescent gynecology. The Journal draws on expertise from a variety of disciplines including pediatrics, obstetrics and gynecology, reproduction and gynecology, reproductive and pediatric endocrinology, genetics, and molecular biology. The Journal of Pediatric and Adolescent Gynecology features original studies, review articles, book and literature reviews, letters to the editor, and communications in brief. It is an essential resource for the libraries of OB/GYN specialists, as well as pediatricians and primary care physicians.
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