Will I feel better? Raising the bar for quality of life in oncology

IF 82.2 1区医学 Q1 ONCOLOGY

Nature Reviews Clinical Oncology Pub Date : 2025-02-28 DOI:10.1038/s41571-025-01002-4

Ariadna Tibau, Alejandra Romano, Aaron S. Kesselheim

引用次数: 0

Abstract

Patients with advanced-stage cancer seek treatments that prolong survival and improve quality of life. We analysed new anticancer drug indications approved by the FDA and EMA between 2020 and 2023 using the European Society for Medical Oncology-Magnitude of Clinical Benefit Scale quality-of-life checklist. Our findings highlight critical gaps in the availability and reliability of quality-of-life outcomes from the pivotal trials that support these approvals.

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我会感觉好点吗？提高肿瘤患者的生活质量

晚期癌症患者寻求能延长生存期并改善生活质量的治疗方法。我们使用欧洲肿瘤内科学会临床获益量表（European Society for Medical Oncology-Magnitude of Clinical Benefit Scale）生活质量检查表分析了美国食品药品管理局（FDA）和欧洲医学管理局（EMA）在 2020 年至 2023 年期间批准的新抗癌药物适应症。我们的研究结果凸显了支持这些批准的关键性试验在生活质量结果的可用性和可靠性方面存在的重大差距。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Clinical Oncology 医学-肿瘤学

CiteScore

99.40

自引率

0.40%

发文量

114

审稿时长

6-12 weeks

期刊介绍： Nature Reviews publishes clinical content authored by internationally renowned clinical academics and researchers, catering to readers in the medical sciences at postgraduate levels and beyond. Although targeted at practicing doctors, researchers, and academics within specific specialties, the aim is to ensure accessibility for readers across various medical disciplines. The journal features in-depth Reviews offering authoritative and current information, contextualizing topics within the history and development of a field. Perspectives, News & Views articles, and the Research Highlights section provide topical discussions, opinions, and filtered primary research from diverse medical journals.