Establishing the role of shear wave elastography in differentiating corporal rigidity between vasculogenic versus non-vasculogenic erectile dysfunction patients.

IF 0.8 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Pushpendra Singh, Aditya Prakash Sharma, Prabhjyot Singh Chowhan, Ujjwal Gorsi, Ravimohan S Mavuduru, Simarjit Singh Rehsi, Anupam Lal, Uttam K Mete
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引用次数: 0

Abstract

Introduction: Shear wave elastography is a new modality for the evaluation of erectile dysfunction by assessing the stiffness of corpora cavernosal tissue. We evaluated the shear wave elastography values in erectile dysfunction participants and compared shear wave elastography values between vasculogenic and non-vasculogenic erectile dysfunction participants.

Methods: Overall, 40 participants with clinically diagnosed erectile dysfunction filled out an abridged five-item version of the international index of erectile dysfunction-5 questionnaire and underwent shear wave elastography as well as pharmacologically induced penile erection test after intracavernosal papaverine injection. Shear wave elastography values were obtained serially at 5-minute interval at two locations: Central (cavernosal artery centered circular region) and Peripheral (near the tunica albuginea). Shear wave elastography values were compared with the erectile dysfunction subtypes.

Results: Median international index of erectile dysfunction-5 score was 11 (interquartile range: 9-14). Median central shear wave elastography values were significantly lower in the erectile state as compared to flaccid state in both vasculogenic (8.27 kPa (interquartile range: 6.3-12.5) vs 23.27 kPa (interquartile range: 15.9-28.6) p = 0.000) and non-vasculogenic (5.50 kPa (interquartile range: 4.4-6.7) vs 23.85 kPa (interquartile range: 17.8-33.6) p = 0.000) erectile dysfunction participants. Vasculogenic erectile dysfunction participants had significantly higher central shear wave elastography value in erectile state than non-vasculogenic erectile dysfunction participants (8.27 kPa (interquartile range: 6.3-12.5) vs 5.50 kPa (interquartile range: 4.4-6.7) p = 0.001). Receiver operating characteristics curve analysis revealed that the cut-off value for central shear wave elastography was 5.65 kPa in erectile state with the sensitivity, and specificity for predicting vasculogenic erectile dysfunction being 90.9% and 61.1%, respectively (area under the curve -0.816; standard error of 0.071 (p = 0.001)).

Conclusion: Central cavernosal shear wave elastography is a good modality to objectively quantify the penile rigidity and can be used to distinguish the subtype of ED.

建立横波弹性成像在区分血管源性与非血管源性勃起功能障碍患者体刚性中的作用。
剪切波弹性成像是一种通过评估海绵体组织刚度来评估勃起功能障碍的新方法。我们评估了勃起功能障碍参与者的横波弹性成像值,并比较了血管源性和非血管源性勃起功能障碍参与者的横波弹性成像值。方法:总共有40名临床诊断为勃起功能障碍的参与者填写了一份国际勃起功能障碍指数5问卷,并在海绵体内注射罂粟碱后进行了横波弹性成像和药理学诱导的阴茎勃起试验。在中央(海绵体动脉为中心的圆形区域)和外周(白膜附近)两个位置连续每隔5分钟获得横波弹性成像值。将横波弹性成像值与勃起功能障碍亚型进行比较。结果:国际勃起功能障碍指数-5评分中位数为11(四分位数范围:9-14)。在血管源性勃起功能障碍(8.27 kPa(四分位数范围:6.3-12.5)vs 23.27 kPa(四分位数范围:15.9-28.6)p = 0.000)和非血管源性勃起功能障碍(5.50 kPa(四分位数范围:4.4-6.7)vs 23.85 kPa(四分位数范围:17.8-33.6)p = 0.000)参与者中,勃起状态的中央横波弹性成像值中位数明显低于松弛状态。血管源性勃起功能障碍受试者在勃起状态下的中央横波弹性成像值明显高于非血管源性勃起功能障碍受试者(8.27 kPa(四分位数范围:6.3-12.5)vs 5.50 kPa(四分位数范围:4.4-6.7)p = 0.001)。受试者工作特征曲线分析显示,勃起状态中央横波弹性成像截断值为5.65 kPa,预测血管源性勃起功能障碍的敏感性和特异性分别为90.9%和61.1%(曲线下面积-0.816;标准误差为0.071 (p = 0.001)。结论:中央海绵体横波弹性成像是一种客观量化阴茎刚性的良好方法,可用于区分ED的亚型。
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来源期刊
Ultrasound
Ultrasound RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.70
自引率
0.00%
发文量
55
期刊介绍: Ultrasound is the official journal of the British Medical Ultrasound Society (BMUS), a multidisciplinary, charitable society comprising radiologists, obstetricians, sonographers, physicists and veterinarians amongst others.
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