Hydroxyurea-related ileocecal region ulcers as a rare complication: A case report.

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

World Journal of Clinical Cases Pub Date : 2025-02-26 DOI:10.12998/wjcc.v13.i6.94330

Wen-Jin Yuan, Yi-Juan Zheng, Bing-Rong Zhang, Yi-Jie Lin, You Li, Yan-Yan Qiu, Xue-Ping Yu

引用次数: 0

Abstract

Background: Hydroxyurea, an antimetabolite, is frequently prescribed for various hematological disorders, and its common side effects include gastrointestinal problems, cutaneous or mucosal lesions and pyrexia/fever.

Case summary: This study reports the case of a 67-year-old woman who developed recurrent abdominal pain after 10 years of continuous hydroxyurea therapy for primary thrombocythemia. Colonoscopy revealed an ileocecal ulcer. After discontinuing hydroxyurea therapy for 6 months, follow-up colonoscopy showed a significant reduction in the ulceration.

Conclusion: We consider cecal ulcers as a rare complication of hydroxyurea therapy which typically resolves upon stopping the drug.

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来源期刊

World Journal of Clinical Cases Medicine-General Medicine

自引率

0.00%

发文量

3384

期刊介绍： The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.