{"title":"Pathogenesis of Orofacial Pain Based on Brain Circuits.","authors":"Takahiko Nagamine","doi":"10.1111/odi.15299","DOIUrl":null,"url":null,"abstract":"<p><p>Orofacial pain is comprised of three distinct components: sensory, perception, and experience or memory. Each of these components is associated with its own specific brain circuit, thereby classifying orofacial pain into three distinct circuits: \"peripheral pain,\" \"brain network pain,\" and \"memorized pain.\" Individuals afflicted with chronic orofacial pain of unknown etiology exhibit characteristics indicative of both brain network pain and memorized pain, necessitating a biopsychosocial approach that takes into account psychosocial factors in addition to the sensory aspects of pain.</p>","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/odi.15299","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Orofacial pain is comprised of three distinct components: sensory, perception, and experience or memory. Each of these components is associated with its own specific brain circuit, thereby classifying orofacial pain into three distinct circuits: "peripheral pain," "brain network pain," and "memorized pain." Individuals afflicted with chronic orofacial pain of unknown etiology exhibit characteristics indicative of both brain network pain and memorized pain, necessitating a biopsychosocial approach that takes into account psychosocial factors in addition to the sensory aspects of pain.
期刊介绍:
Oral Diseases is a multidisciplinary and international journal with a focus on head and neck disorders, edited by leaders in the field, Professor Giovanni Lodi (Editor-in-Chief, Milan, Italy), Professor Stefano Petti (Deputy Editor, Rome, Italy) and Associate Professor Gulshan Sunavala-Dossabhoy (Deputy Editor, Shreveport, LA, USA). The journal is pre-eminent in oral medicine. Oral Diseases specifically strives to link often-isolated areas of dentistry and medicine through broad-based scholarship that includes well-designed and controlled clinical research, analytical epidemiology, and the translation of basic science in pre-clinical studies. The journal typically publishes articles relevant to many related medical specialties including especially dermatology, gastroenterology, hematology, immunology, infectious diseases, neuropsychiatry, oncology and otolaryngology. The essential requirement is that all submitted research is hypothesis-driven, with significant positive and negative results both welcomed. Equal publication emphasis is placed on etiology, pathogenesis, diagnosis, prevention and treatment.