End-tidal carbon monoxide for routine monitoring of significant hemolysis in the management of newborn hyperbilirubinemia.

IF 2.4 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Journal of Perinatology Pub Date : 2025-02-26 DOI:10.1038/s41372-025-02242-z

Shanice Wells, Ramya Balasubramanian, Khang Nguyen, David L Schutzman

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引用次数: 0

Abstract

Objective: Assess the efficacy of routine ETCOc for all newborns in managing neonatal hyperbilirubinemia.

Study design: Retrospective chart review of 1029 consecutive well-baby nursery admissions following the 2022 AAP hyperbilirubinemia guidelines. Only ETCOc, not type, Rh, and DAT, was used to determine if significant hemolysis was present in sufficient degree to affect bilirubin management. A cost-benefit analysis comparing the two methods was conducted.

Result: 2.8% of infants required phototherapy, and 1.1% were readmitted for hyperbilirubinemia. The closer an infant's bilirubin level was to the phototherapy threshold, the higher the ETCOc. 12 of 29 DAT negative infants with ETCOc ≥ 2.5 PPM who received phototherapy would have gone home with significant hemolysis at risk for readmission or kernicterus if not for the use of ETCOc.

Conclusion: ETCOc is preferable for assessing significant hemolysis in the newborn, can be used to safely manage newborn hyperbilirubinemia, and results in cost savings.

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来源期刊

Journal of Perinatology 医学-妇产科学

CiteScore

5.40

自引率

6.90%

发文量

284

审稿时长

3-8 weeks

期刊介绍： The Journal of Perinatology provides members of the perinatal/neonatal healthcare team with original information pertinent to improving maternal/fetal and neonatal care. We publish peer-reviewed clinical research articles, state-of-the art reviews, comments, quality improvement reports, and letters to the editor. Articles published in the Journal of Perinatology embrace the full scope of the specialty, including clinical, professional, political, administrative and educational aspects. The Journal also explores legal and ethical issues, neonatal technology and product development. The Journal’s audience includes all those that participate in perinatal/neonatal care, including, but not limited to neonatologists, perinatologists, perinatal epidemiologists, pediatricians and pediatric subspecialists, surgeons, neonatal and perinatal nurses, respiratory therapists, pharmacists, social workers, dieticians, speech and hearing experts, other allied health professionals, as well as subspecialists who participate in patient care including radiologists, laboratory medicine and pathologists.