Time is spine: critical updates for the intensivist.

IF 3.4 3区 医学 Q1 CRITICAL CARE MEDICINE
Current Opinion in Critical Care Pub Date : 2025-04-01 Epub Date: 2025-02-27 DOI:10.1097/MCC.0000000000001245
Ryan Sandarage, Joseph Y Nashed, Eve C Tsai
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引用次数: 0

Abstract

Purpose of review: The concept of 'time is spine' emphasizes early or ultra-early surgical decompression within 24 or 12 h, respectively, after spinal cord injury (SCI) to maximize recovery. This review updates the latest findings on the timing of surgical decompression and hemodynamic management in acute SCI, focusing on neurological outcomes and complications.

Recent findings: While early decompression may improve neurological outcomes, factors like injury severity, comorbidities, and system resources affect surgical timing. Recent studies question the benefits of ultra-early decompression, finding no significant improvement at 12 months, suggesting earlier analyses may have overstated its benefits. Current recommendations include tailoring decompression timing to individual cases, considering patient-specific and systemic factors. New techniques like spinal cord pressure monitoring, intraoperative ultrasound, and advanced imaging are advancing targeted intervention and hemodynamic management in SCI.

Summary: The timing of spinal decompression and hemodynamic management may impact neurological function, however, because of the deficiencies of current studies, individualized, patient-tailored decision-making is critical. A multidisciplinary approach that considers injury severity and patient characteristics is essential for optimal management. Further research is required to refine the timing of surgical intervention and explore additional factors influencing recovery.

Abstract Image

时间就是脊柱:对重症医生来说,这是关键的更新。
回顾目的:“时间就是脊柱”的概念强调在脊髓损伤(SCI)后24小时或12小时内分别进行早期或超早期手术减压,以最大限度地恢复。这篇综述更新了急性脊髓损伤手术减压时机和血流动力学治疗的最新发现,重点是神经预后和并发症。近期研究发现:虽然早期减压可以改善神经系统预后,但损伤严重程度、合并症和系统资源等因素会影响手术时机。最近的研究质疑了超早期减压的好处,发现在12个月后没有明显的改善,这表明早期的分析可能夸大了它的好处。目前的建议包括根据个别病例调整减压时间,考虑患者特异性和全身因素。脊髓压力监测、术中超声和先进成像等新技术正在推进脊髓损伤的靶向干预和血流动力学管理。摘要:脊柱减压和血流动力学治疗的时机可能会影响神经功能,然而,由于目前研究的不足,个性化的、针对患者的决策是至关重要的。考虑损伤严重程度和患者特征的多学科方法对于最佳管理至关重要。需要进一步的研究来完善手术干预的时机,并探索影响恢复的其他因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current Opinion in Critical Care
Current Opinion in Critical Care 医学-危重病医学
CiteScore
5.90
自引率
3.00%
发文量
172
审稿时长
6-12 weeks
期刊介绍: ​​​​​​​​​Current Opinion in Critical Care delivers a broad-based perspective on the most recent and most exciting developments in critical care from across the world. Published bimonthly and featuring thirteen key topics – including the respiratory system, neuroscience, trauma and infectious diseases – the journal’s renowned team of guest editors ensure a balanced, expert assessment of the recently published literature in each respective field with insightful editorials and on-the-mark invited reviews.
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