Application of injectable platelet-rich fibrin (I-PRF) after posterior tooth removal surgery: a systematic review.

IF 1.4 4区医学 Q4 CELL BIOLOGY

Cell and Tissue Banking Pub Date : 2025-02-27 DOI:10.1007/s10561-025-10160-9

Ilan Hudson Gomes de Santana, Mayara Rebeca Martins Viana, Julliana Cariry Palhano Dias, Anderson Jara Ferreira, Eduardo Sant'Ana, Eduardo Dias Ribeiro

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Abstract

Injectable platelet-rich fibrin (I-PRF) is primarily found in liquid form and plays a role in accelerating vascularization and aiding wound healing. To carry out a critical analysis of the therapeutic potential of injectable platelet-rich fibrin (I-PRF) in the postoperative management of these surgeries. The systematic review protocol for this study included start and end dates, research question, databases, PICO structure, search strategy, inclusion/exclusion criteria, types of studies, measures of effect, screening methods, data extraction/analysis and risk of bias assessment tools. Registered with PROSPERO (CRD42024537367), it guaranteed transparency and quality. Searches were carried out on the PubMed, Scopus, Embase, Wiley Online Library and Web of Science databases. Results: The systematic search in the databases identified 532 studies. After removing duplicates with Rayyan© software, 480 documents remained, of which 15 met the inclusion criteria. After evaluation following the review protocol, 5 studies were considered highly relevant and included in the systematic review. The results indicated not only uncomplicated healing and adequate osseointegration, but also a significant improvement in comfort parameters and post-operative recovery. It was observed that the application of I-PRF accelerated the healing process, reduced pain and edema, and improved soft and hard tissue regeneration.

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来源期刊

Cell and Tissue Banking CELL BIOLOGY-ENGINEERING, BIOMEDICAL

CiteScore

3.10

自引率

13.30%

发文量

审稿时长

6-12 weeks

期刊介绍： Cell and Tissue Banking provides a forum for disseminating information to scientists and clinicians involved in the banking and transplantation of cells and tissues. Cell and Tissue Banking is an international, peer-reviewed journal that publishes original papers in the following areas: basic research concerning general aspects of tissue banking such as quality assurance and control of banked cells/tissues, effects of preservation and sterilisation methods on cells/tissues, biotechnology, etc.; clinical applications of banked cells/tissues; standards of practice in procurement, processing, storage and distribution of cells/tissues; ethical issues; medico-legal issues.