Application of injectable platelet-rich fibrin (I-PRF) after posterior tooth removal surgery: a systematic review.

IF 1.4 4区医学 Q4 CELL BIOLOGY

Cell and Tissue Banking Pub Date : 2025-02-27 DOI:10.1007/s10561-025-10160-9

Ilan Hudson Gomes de Santana, Mayara Rebeca Martins Viana, Julliana Cariry Palhano Dias, Anderson Jara Ferreira, Eduardo Sant'Ana, Eduardo Dias Ribeiro

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引用次数: 0

Abstract

Injectable platelet-rich fibrin (I-PRF) is primarily found in liquid form and plays a role in accelerating vascularization and aiding wound healing. To carry out a critical analysis of the therapeutic potential of injectable platelet-rich fibrin (I-PRF) in the postoperative management of these surgeries. The systematic review protocol for this study included start and end dates, research question, databases, PICO structure, search strategy, inclusion/exclusion criteria, types of studies, measures of effect, screening methods, data extraction/analysis and risk of bias assessment tools. Registered with PROSPERO (CRD42024537367), it guaranteed transparency and quality. Searches were carried out on the PubMed, Scopus, Embase, Wiley Online Library and Web of Science databases. Results: The systematic search in the databases identified 532 studies. After removing duplicates with Rayyan© software, 480 documents remained, of which 15 met the inclusion criteria. After evaluation following the review protocol, 5 studies were considered highly relevant and included in the systematic review. The results indicated not only uncomplicated healing and adequate osseointegration, but also a significant improvement in comfort parameters and post-operative recovery. It was observed that the application of I-PRF accelerated the healing process, reduced pain and edema, and improved soft and hard tissue regeneration.

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可注射富血小板纤维蛋白（I-PRF）在后牙拔除手术后的应用：系统回顾。

可注射的富血小板纤维蛋白（I-PRF）主要以液体形式存在，在加速血管形成和帮助伤口愈合方面发挥作用。对可注射富血小板纤维蛋白（I-PRF）在这些手术的术后管理中的治疗潜力进行批判性分析。本研究的系统评价方案包括开始和结束日期、研究问题、数据库、PICO结构、检索策略、纳入/排除标准、研究类型、效果测量、筛选方法、数据提取/分析和偏倚风险评估工具。在普洛斯彼罗注册（CRD42024537367），它保证了透明度和质量。在PubMed、Scopus、Embase、Wiley Online Library和Web of Science数据库上进行了搜索。结果：在数据库中系统检索到532项研究。在使用Rayyan©软件删除重复后，保留了480份文档，其中15份符合纳入标准。根据评价方案进行评价后，5项研究被认为高度相关并纳入系统评价。结果表明，不仅愈合简单，骨融合良好，而且舒适度和术后恢复也有明显改善。观察到I-PRF的应用加速了愈合过程，减轻了疼痛和水肿，改善了软硬组织的再生。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell and Tissue Banking CELL BIOLOGY-ENGINEERING, BIOMEDICAL

CiteScore

3.10

自引率

13.30%

发文量

审稿时长

6-12 weeks

期刊介绍： Cell and Tissue Banking provides a forum for disseminating information to scientists and clinicians involved in the banking and transplantation of cells and tissues. Cell and Tissue Banking is an international, peer-reviewed journal that publishes original papers in the following areas: basic research concerning general aspects of tissue banking such as quality assurance and control of banked cells/tissues, effects of preservation and sterilisation methods on cells/tissues, biotechnology, etc.; clinical applications of banked cells/tissues; standards of practice in procurement, processing, storage and distribution of cells/tissues; ethical issues; medico-legal issues.