Volumetric measurement of cranial cavity and cerebral ventricular system with 3D Slicer software based on CT data.

IF 2.9 3区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Yanming Huang, Junxiang Huang, Celin Guan, Tianqing Liu, Shuanglin Que
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引用次数: 0

Abstract

Objective: This study aims to evaluate the clinical utility of using 3D Slicer software for volumetric measurement of the cranial cavity and cerebral ventricular system, particularly in hydrocephalus patients. We also provide detailed steps for performing the measurements.

Methods: Volumetric measurements were performed on 186 healthy volunteers, 117 hydrocephalus patients with intact skulls, and 72 hydrocephalus patients with incomplete skulls using 3D Slicer based on computed tomography (CT) data. CT scans were performed using a GE Discovery750 scanner and analyzed with 3D Slicer software (version 5.0.2). Cranial cavity volumes were measured using two methods: the Swiss Skull Stripper module and the Segment Editor tool. Ventricular volumes were assessed by segmenting the ventricles and periventricular structures with anatomical markers. Data were analyzed for consistency and accuracy using SPSS version 25.0, with statistical significance set at p ≤ 0.05.

Results: Intracranial volume measurements showed no significant differences between healthy controls and HANPH patients, nor between different measurement methods. In healthy controls, males had larger ventricular volumes than females, and older individuals had larger volumes, except for the fourth ventricle. The left lateral ventricle was larger than the right. No discrepancies were found between measurements taken by two neurosurgeons.

Conclusion: The volumetric measurement of cranial cavity and cerebral ventricular system with 3D Slicer software based on CT data are accurate, repeatable and consistent, providing methodological and technical support for hydrocephalus research, especially for incomplete skull patients, the third ventricle and the fourth ventricle.

Clinical trial number: Not applicable.

基于CT数据的三维切片软件颅内及脑室系统体积测量。
目的:本研究旨在评估使用3D切片软件进行颅腔和脑室系统体积测量的临床应用,特别是在脑积水患者中。我们还提供了执行测量的详细步骤。方法:采用基于计算机断层扫描(CT)数据的三维切片机对186名健康志愿者、117例颅骨完整的脑积水患者和72例颅骨不完整的脑积水患者进行体积测量。使用GE Discovery750扫描仪进行CT扫描,并使用3D Slicer软件(版本5.0.2)进行分析。颅腔体积测量采用两种方法:Swiss Skull Stripper模块和Segment Editor工具。通过解剖标记分割心室和心室周围结构来评估心室容积。采用SPSS 25.0版本对数据进行一致性和准确性分析,p≤0.05为统计学显著性。结果:颅内体积测量在健康对照组和HANPH患者之间无显著差异,不同测量方法之间也无显著差异。在健康对照中,男性的心室容积大于女性,老年人的心室容积大于女性,但第四心室除外。左侧脑室大于右侧脑室。两位神经外科医生所做的测量没有发现差异。结论:3D Slicer软件基于CT数据对颅腔和脑室系统的体积测量准确、可重复性好、一致性好,为脑积水研究,特别是对颅骨不全患者、第三脑室和第四脑室的研究提供了方法学和技术支持。临床试验号:不适用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMC Medical Imaging
BMC Medical Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
4.60
自引率
3.70%
发文量
198
审稿时长
27 weeks
期刊介绍: BMC Medical Imaging is an open access journal publishing original peer-reviewed research articles in the development, evaluation, and use of imaging techniques and image processing tools to diagnose and manage disease.
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