Rachele K. Lipsky , Drew A. Helmer , Jean C. Beckham , Patrick S. Calhoun , Mary Jo Pugh , Nathan A. Kimbrel
{"title":"The association between Gulf War Illness and suicidal thoughts and behaviors among Gulf War Era Veterans","authors":"Rachele K. Lipsky , Drew A. Helmer , Jean C. Beckham , Patrick S. Calhoun , Mary Jo Pugh , Nathan A. Kimbrel","doi":"10.1016/j.jpsychires.2025.02.039","DOIUrl":null,"url":null,"abstract":"<div><div>The rate of death by suicide is elevated among Veterans of all eras. Chronic symptoms of pain, depression, and sleep disturbances are also common among Veterans, and these symptoms are associated with suicidal thoughts and behaviors. About 25% of the 697,000 Gulf War Era Veterans deployed to the Persian Gulf theater in 1990–1991 remain afflicted with chronic, unexplained symptoms known as Gulf War Illness (GWI). This study used data from a national sample of Gulf War Veterans (N = 1142) who completed a survey of demographic, military, and health information. Multivariable logistic regression models, controlling for confounding variables, tested for associations between deployment, a tri-level categorical variable of GWI (no GWI; moderate GWI; and severe GWI) and suicidal thoughts and behaviors. Deployment was not associated with any suicide related outcome. Moderate and severe GWI remained significantly associated with past year suicidal ideation (moderate GWI: aOR 3.94; 95% CI: 1.55–10.03; severe GWI: aOR 3.66; 95% CI: 1.31–10.20), but they were not associated with suicide attempts. Our findings suggest that the burden and negative impact of the chronic symptoms of GWI may play a role in the occurrence of suicidal ideation in Gulf War Veterans (GWV). Clinicians caring for GWVs should attend to both chronic symptoms, and the elevated risk of suicidal thoughts in this cohort.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"183 ","pages":"Pages 302-307"},"PeriodicalIF":3.7000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of psychiatric research","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0022395625001189","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0
Abstract
The rate of death by suicide is elevated among Veterans of all eras. Chronic symptoms of pain, depression, and sleep disturbances are also common among Veterans, and these symptoms are associated with suicidal thoughts and behaviors. About 25% of the 697,000 Gulf War Era Veterans deployed to the Persian Gulf theater in 1990–1991 remain afflicted with chronic, unexplained symptoms known as Gulf War Illness (GWI). This study used data from a national sample of Gulf War Veterans (N = 1142) who completed a survey of demographic, military, and health information. Multivariable logistic regression models, controlling for confounding variables, tested for associations between deployment, a tri-level categorical variable of GWI (no GWI; moderate GWI; and severe GWI) and suicidal thoughts and behaviors. Deployment was not associated with any suicide related outcome. Moderate and severe GWI remained significantly associated with past year suicidal ideation (moderate GWI: aOR 3.94; 95% CI: 1.55–10.03; severe GWI: aOR 3.66; 95% CI: 1.31–10.20), but they were not associated with suicide attempts. Our findings suggest that the burden and negative impact of the chronic symptoms of GWI may play a role in the occurrence of suicidal ideation in Gulf War Veterans (GWV). Clinicians caring for GWVs should attend to both chronic symptoms, and the elevated risk of suicidal thoughts in this cohort.
期刊介绍:
Founded in 1961 to report on the latest work in psychiatry and cognate disciplines, the Journal of Psychiatric Research is dedicated to innovative and timely studies of four important areas of research:
(1) clinical studies of all disciplines relating to psychiatric illness, as well as normal human behaviour, including biochemical, physiological, genetic, environmental, social, psychological and epidemiological factors;
(2) basic studies pertaining to psychiatry in such fields as neuropsychopharmacology, neuroendocrinology, electrophysiology, genetics, experimental psychology and epidemiology;
(3) the growing application of clinical laboratory techniques in psychiatry, including imagery and spectroscopy of the brain, molecular biology and computer sciences;