Polyoxometalate decorated graphene oxides sheets for simultaneous non-enzymatic electrochemical detection of biomolecules

IF 4.3 3区材料科学 Q2 MATERIALS SCIENCE, COATINGS & FILMS

Diamond and Related Materials Pub Date : 2025-02-25 DOI:10.1016/j.diamond.2025.112148

Rehana Zia , Muhammad Ahmad , Maryam Kaleem , Salih Akyürekli , Sadaf Ul Hassan , Osama A. Mohammed , Fatimah M. Alzahrani , Munawar Iqbal , Abid Ali

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Abstract

A novel Wells-Dawson type Polyoxometalates (POM) in combination with graphene oxide (GO) has been developed as a non-enzymatic electrochemical sensor for the detection of ascorbic acid and uric acid. The electrochemical detection of these biomolecules is crucial in biomedical analysis, offering high sensitivity, selectivity, and rapid detection. This method significantly contributes to physiology, disease diagnostics, therapeutic monitoring, and the advancement of portable biosensor technologies. As prepared POM@GO composite was characterized using various techniques including X-ray diffraction crystallography (XRD), Fourier-transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM) and energy dispersive x-ray (EDX) spectroscopy to confirm the functional groups, crystal structure, morphology and elemental composition, respectively. Uniformly dispersed POM over conductively efficient GO boosted the catalytic performance synergies via active site and enlarge surface area provided by the POM and GO, respectively. As fabricated composite improved sensitivity towards individual and simultaneous electrochemical detection of ascorbic acid and uric acid. POM@GO over glassy carbon electrode showed a higher sensitivity of 10.24 μAcm⁻² mM⁻¹ and 5.27 μAcm⁻² mM⁻¹, lower detection limit of 46 μM and 47 μM and a linear range of up to 1.5 mM for AA and UA, respectively.

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来源期刊

Diamond and Related Materials 工程技术-材料科学：综合

CiteScore

6.00

自引率

14.60%

发文量

702

审稿时长

2.1 months

期刊介绍： DRM is a leading international journal that publishes new fundamental and applied research on all forms of diamond, the integration of diamond with other advanced materials and development of technologies exploiting diamond. The synthesis, characterization and processing of single crystal diamond, polycrystalline films, nanodiamond powders and heterostructures with other advanced materials are encouraged topics for technical and review articles. In addition to diamond, the journal publishes manuscripts on the synthesis, characterization and application of other related materials including diamond-like carbons, carbon nanotubes, graphene, and boron and carbon nitrides. Articles are sought on the chemical functionalization of diamond and related materials as well as their use in electrochemistry, energy storage and conversion, chemical and biological sensing, imaging, thermal management, photonic and quantum applications, electron emission and electronic devices. The International Conference on Diamond and Carbon Materials has evolved into the largest and most well attended forum in the field of diamond, providing a forum to showcase the latest results in the science and technology of diamond and other carbon materials such as carbon nanotubes, graphene, and diamond-like carbon. Run annually in association with Diamond and Related Materials the conference provides junior and established researchers the opportunity to exchange the latest results ranging from fundamental physical and chemical concepts to applied research focusing on the next generation carbon-based devices.