The dietary inflammatory potential and its role in the risk and progression of inflammatory bowel disease: A systematic review

IF 6.6 2区医学 Q1 NUTRITION & DIETETICS

Clinical nutrition Pub Date : 2025-02-19 DOI:10.1016/j.clnu.2025.02.019

Olivia Mariella Anneberg , Ida Sofie Bjerregård Petersen , Tine Jess , Maiara Brusco De Freitas , Mahsa Jalili

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引用次数: 0

Abstract

Background & aims

Inflammation is central in inflammatory bowel disease (IBD) pathogenesis. Because of diet's pro- and anti-inflammatory properties, multiple observational studies have explored the link between the dietary inflammatory potential and IBD-related outcomes. We aimed to systematically review the literature and provide a comprehensive overview of the dietary inflammatory potential and its association with the development and progression of IBD.

Methods

Literature was searched systematically on the 2nd of May 2024 in PubMed, Web of Science, Scopus, Cochrane Library, and Embase to identify the observational studies that explored the link between the dietary inflammatory potential and IBD-related outcomes. A higher dietary inflammatory potential was defined as the ability of a dietary pattern to promote inflammation in the body. Studies were included only if they quantified this using a dietary index, such as the dietary inflammatory index (DII) and the empirical dietary inflammatory pattern (EDIP). Two authors independently performed study selection and data extraction and assessed the risk of bias using the Newcastle-Ottawa scale.

Results

Fourteen of the 165 identified records met the inclusion criteria. Seven investigated the risk of developing IBD, but with mixed results. Nine investigated the progression of IBD, which indicated that a higher dietary inflammatory potential contributed to higher disease activity and associated symptoms.

Conclusions

The evidence suggested that a higher dietary inflammatory potential worsens the condition of IBD patients, while the link with the risk of developing the disease was less clear. To elucidate this, high-quality intervention studies are needed.

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饮食炎症潜能及其在炎症性肠病风险和进展中的作用：系统综述

背景,目的炎症是炎症性肠病（IBD）发病机制的核心。由于饮食的促炎和抗炎特性，多项观察性研究探索了饮食炎症潜力与ibd相关结果之间的联系。我们旨在系统地回顾文献，全面概述饮食炎症潜力及其与IBD发展和进展的关系。方法系统检索2024年5月2日PubMed、Web of Science、Scopus、Cochrane Library和Embase的文献，以确定探索饮食炎症潜力与ibd相关结果之间联系的观察性研究。较高的饮食炎症潜力被定义为一种饮食模式促进体内炎症的能力。只有使用膳食指数（如膳食炎症指数（DII）和经验膳食炎症模式（EDIP））对其进行量化的研究才被纳入。两位作者独立进行了研究选择和数据提取，并使用纽卡斯尔-渥太华量表评估了偏倚风险。结果165份鉴定记录中有14份符合纳入标准。7项研究调查了患IBD的风险，但结果好坏参半。9项研究调查了IBD的进展，这表明较高的饮食炎症潜力导致较高的疾病活动性和相关症状。结论：有证据表明，较高的饮食炎症潜力会恶化IBD患者的病情，但与患病风险的联系尚不清楚。为了阐明这一点，需要进行高质量的干预研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical nutrition 医学-营养学

CiteScore

14.10

自引率

6.30%

发文量

356

审稿时长

28 days

期刊介绍： Clinical Nutrition, the official journal of ESPEN, The European Society for Clinical Nutrition and Metabolism, is an international journal providing essential scientific information on nutritional and metabolic care and the relationship between nutrition and disease both in the setting of basic science and clinical practice. Published bi-monthly, each issue combines original articles and reviews providing an invaluable reference for any specialist concerned with these fields.