Daytime napping and risk of incident main adverse cardiovascular events and mortality among adults with type 2 diabetes

IF 6.1 3区医学 Q1 ENDOCRINOLOGY & METABOLISM

Diabetes research and clinical practice Pub Date : 2025-02-25 DOI:10.1016/j.diabres.2025.112067

Xiu Hong Yang , Yao Liu , Xin Xin Jiang , Zhen Xing Zhang , Yi Jun Lu , Chen Sheng Fu , Hui Min Jin , Zhi Bin Ye

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引用次数: 0

Abstract

Aims

To explore the link between daytime napping and the risk of major adverse cardiovascular events (MACE) and mortality in individuals with type 2 diabetes.

Methods

This prospective study included 21,129 participants with diabetes from the UK Biobank, all of whom were free of MACE and cancer at baseline. Data on habitual daytime napping and sleep duration were collected via a baseline questionnaire. Cox proportional hazards regression models were employed to assess the relationship between daytime napping and MACE, all-cause mortality, and cardiovascular disease (CVD) specific mortality. MACE was defined as a composite of myocardial infarction, heart failure, and stroke.

Results

Over an average 11.9-year follow-up, 5,611 MACE cases, 3,854 all-cause deaths, and 1,839 CVD deaths were identified. Compared to those who never/rarely napped, the multivariable-adjusted hazard ratios for usually napping were: 1.39 (1.08, 1.65) for MACE; 1.44 (1.01, 1.92) for myocardial infarction; 1.33 (1.07, 1.64) for heart failure; 1.57 (1.06, 2.33) for stroke; 1.28 (1.01, 1.60) for all-cause mortality; 1.33 (0.97, 1.94) for CVD mortality.

Conclusions

Frequent daytime napping is significantly associated with an increased risk of MACE and mortality among individuals with diabetes, particularly those who have extended sleep durations of more than 10 h and severe diabetes.

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来源期刊

Diabetes research and clinical practice 医学-内分泌学与代谢

CiteScore

10.30

自引率

3.90%

发文量

862

审稿时长

32 days

期刊介绍： Diabetes Research and Clinical Practice is an international journal for health-care providers and clinically oriented researchers that publishes high-quality original research articles and expert reviews in diabetes and related areas. The role of the journal is to provide a venue for dissemination of knowledge and discussion of topics related to diabetes clinical research and patient care. Topics of focus include translational science, genetics, immunology, nutrition, psychosocial research, epidemiology, prevention, socio-economic research, complications, new treatments, technologies and therapy.