Jingyi Yang, Yixuan Zhou, Yuankun Cai, Lei Shen, Yuanyuan Ruan, Songshan Chai, Dongyuan Xu, Jianzhang Pu, Hao Du, Nanxiang Xiong
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引用次数: 0
Abstract
Purpose: This case series aimed to investigate the safety and efficacy of medial temporal lobotomy (MTL) in the treatment of medial temporal lobe epilepsy (MTLE).
Methods: We presented our experience with 12 MTLE patients who underwent MTL in our center from January 2018 to July 2021. The MTL technique involves suction-based removal of the amygdala, effectively severing the fibrous connections between the medial temporal lobe structures and the surrounding cortex while maintaining the integrity of the medial temporal lobe structures without removing the hippocampus as in selective amygdalohippocampectomy.
Results: Among the 12 MTLE patients, five were men and seven were women. Mean age was 18.7 years-old, ranging from 6 to 41 years-old. All surgeries were completed successfully. Although one patient developed a transient mild disturbance of consciousness that fully resolved, no patient experienced intracranial hemorrhage, cerebral infarction, hemiplegia, aphasia, or visual field defect. Mean follow-up was 3.25 years, ranging from 6 to 41 years. The Engel classification for seizure outcomes at the last follow-up was as follows: class I, 9 patients (75.0%); class II, 1 patient (8.3%); and class III, 2 patients (16.7%).
Conclusion: Our preliminary results show that MTL is safe and effective. Future studies are warranted to validate our outcomes.
期刊介绍:
The goal of Neurosurgical Review is to provide a forum for comprehensive reviews on current issues in neurosurgery. Each issue contains up to three reviews, reflecting all important aspects of one topic (a disease or a surgical approach). Comments by a panel of experts within the same issue complete the topic. By providing comprehensive coverage of one topic per issue, Neurosurgical Review combines the topicality of professional journals with the indepth treatment of a monograph. Original papers of high quality are also welcome.