Morphological characteristics of developmental anomalies of the thyroid gland: a prospective single-center cohort study.

IF 1.2 4区医学 Q3 ANATOMY & MORPHOLOGY

Folia morphologica Pub Date : 2025-02-26 DOI:10.5603/fm.102943

Iryna Samec, Marek Samec, Gabriela Hešková, Ľubomír Straka, Martin Janík, Desanka Výbohová

{"title":"Morphological characteristics of developmental anomalies of the thyroid gland: a prospective single-center cohort study.","authors":"Iryna Samec, Marek Samec, Gabriela Hešková, Ľubomír Straka, Martin Janík, Desanka Výbohová","doi":"10.5603/fm.102943","DOIUrl":null,"url":null,"abstract":"Background: Thyroid diverticulum originates between the first and second pharyngeal pouches, and descends via the thyroglossal duct to the level of CV to TI vertebra. By the 6th week of gestation the thyroglossal duct starts to obliterate. Failure in its obliteration causes differentiation of the distal part into the pyramidal lobe (PL), while the cranial portion may alter into a fibromuscular remnant - levator glandulae thyreoideae (LGT).Materials and methods: Morphological characteristics of PL and LGT were prospectively observed in 86 cadavers (66 male and 20 female).Results: PL was observed in 59.3%, occurring more frequently in male cadavers (60.61%) compared to female cadavers (55%). PL was more frequent on the left side (50.98%) than on the right side (39.22%). Junctional PL was determined in 58.82%, isthmic PL in 27.45%, and lobar PL in 13.73%. The average height, width, and area of PL reached 23.81 mm, 13.13 mm, and 320.16 mm², respectively. The most frequent height-to-width ratio of PL was 1.3 : 1. LGT was observed in 47.67% of cadavers. LGT prevailed in male cadavers (48.48%) over female cadavers (45%). LGT occurred commonly on the left side (53.66%) than on the right side (31.71 %). Macroscopic evaluation demonstrated prevalence of fibrous LGTs (65.85%). Hyopyramidal type of LGT was observed in 70.73% of cadavers.Conclusions: Knowledge gained from this study is applicable in the surgical field to reduce the risk of intraoperative and postoperative complications in thyroid surgery.","PeriodicalId":12251,"journal":{"name":"Folia morphologica","volume":" ","pages":""},"PeriodicalIF":1.2000,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Folia morphologica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5603/fm.102943","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ANATOMY & MORPHOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Thyroid diverticulum originates between the first and second pharyngeal pouches, and descends via the thyroglossal duct to the level of CV to TI vertebra. By the 6th week of gestation the thyroglossal duct starts to obliterate. Failure in its obliteration causes differentiation of the distal part into the pyramidal lobe (PL), while the cranial portion may alter into a fibromuscular remnant - levator glandulae thyreoideae (LGT).

Materials and methods: Morphological characteristics of PL and LGT were prospectively observed in 86 cadavers (66 male and 20 female).

Results: PL was observed in 59.3%, occurring more frequently in male cadavers (60.61%) compared to female cadavers (55%). PL was more frequent on the left side (50.98%) than on the right side (39.22%). Junctional PL was determined in 58.82%, isthmic PL in 27.45%, and lobar PL in 13.73%. The average height, width, and area of PL reached 23.81 mm, 13.13 mm, and 320.16 mm², respectively. The most frequent height-to-width ratio of PL was 1.3 : 1. LGT was observed in 47.67% of cadavers. LGT prevailed in male cadavers (48.48%) over female cadavers (45%). LGT occurred commonly on the left side (53.66%) than on the right side (31.71 %). Macroscopic evaluation demonstrated prevalence of fibrous LGTs (65.85%). Hyopyramidal type of LGT was observed in 70.73% of cadavers.

Conclusions: Knowledge gained from this study is applicable in the surgical field to reduce the risk of intraoperative and postoperative complications in thyroid surgery.

查看原文本刊更多论文

甲状腺发育异常的形态学特征：一项前瞻性单中心队列研究。

背景：甲状腺憩室起源于第一和第二咽囊之间，经甲状舌管下降至CV至TI椎体水平。到妊娠第6周，甲状舌管开始消失。其阻塞失败导致远端分化为锥体叶（PL），而颅部可能转变为纤维肌肉残余-提甲状腺腺（LGT）。材料与方法：前瞻性观察86具尸体（男66具，女20具）的左、下丘脑的形态特征。结果：PL发生率为59.3%，男性（60.61%）高于女性（55%）。左侧病变发生率为50.98%，右侧病变发生率为39.22%。关节PL为58.82%，峡部PL为27.45%，肺叶PL为13.73%。PL的平均高度23.81 mm，宽度13.13 mm，面积320.16 mm²。最常见的PL高宽比为1.3:1。47.67%的尸体出现LGT。LGT在男性尸体中占48.48%，在女性尸体中占45%。LGT多发于左侧（53.66%），多发于右侧（31.71%）。宏观评价显示纤维性LGTs患病率（65.85%）。70.73%的尸体为下锥体型LGT。结论：本研究获得的知识可应用于外科领域，降低甲状腺手术术中及术后并发症的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Folia morphologica ANATOMY & MORPHOLOGY-

CiteScore

2.40

自引率

0.00%

发文量

218

审稿时长

6-12 weeks

期刊介绍： "Folia Morphologica" is an official journal of the Polish Anatomical Society (a Constituent Member of European Federation for Experimental Morphology - EFEM). It contains original articles and reviews on morphology in the broadest sense (descriptive, experimental, and methodological). Papers dealing with practical application of morphological research to clinical problems may also be considered. Full-length papers as well as short research notes can be submitted. Descriptive papers dealing with non-mammals, cannot be accepted for publication with some exception.