Antimicrobial use and prescribing practices by equine veterinarians in Australia: Insights into reproduction, dentistry, compounding and use for nonbactericidal effects

IF 1.3 4区农林科学 Q2 VETERINARY SCIENCES

Australian Veterinary Journal Pub Date : 2025-02-25 DOI:10.1111/avj.13428

LY Hardefeldt, K Thomas, L Begg

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引用次数: 0

Abstract

Background

Antimicrobial resistance (AMR) is a problem for equine practitioners in Australia, but antimicrobial use in practice has been largely understudied. We aimed to evaluate equine veterinarians' intentions of prescribing antimicrobials in areas where we perceived there to be wide ranges of practice – dentistry, reproduction and for nonbactericidal effects.

Method

An online cross-sectional survey of veterinarians working in equine practice was conducted over 4 months in 2023 and 2024. Antimicrobial use, including compounding practices, for reproductive and dental disorders, and nonbactericidal effects were investigated.

Results

Responses were received from 134 equine practitioners in Australia. Most respondents reported using common equine antimicrobials (trimethoprim sulphonamide (TMS), penicillin and gentamicin). Low- and medium-importance-rated antimicrobials predominated for dental and reproductive disorders although there were some reported uses of high-importance agents, including some not registered for use in horses. Prescribing compounded antimicrobials was common (70% of respondents). Antimicrobials were also reported to be used for contracted tendons, matrix metalloprotease inhibition, anti-inflammatory and antiendotoxic and other nonbacteriocidal effects.

Conclusion

Although antimicrobial prescribing patterns varied, most respondents reported using common equine antimicrobials. Antimicrobial guidelines may assist in aligning practice and reducing inappropriate antimicrobial use in horses.

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澳大利亚马兽医的抗菌药物使用和处方实践：对生殖，牙科，复合和非杀菌效果使用的见解。

背景：抗菌素耐药性（AMR）是澳大利亚马从业者的一个问题，但抗菌素在实践中的使用在很大程度上尚未得到充分研究。我们的目的是评估马兽医在我们认为有广泛实践的领域——牙科、生殖和非杀菌效果——开抗菌剂处方的意图。方法：对2023年和2024年4个月的马科兽医进行在线横断面调查。抗菌药物的使用，包括复合做法，用于生殖和牙科疾病，和非杀菌效果进行了调查。结果：收到了来自澳大利亚134名马从业者的回复。大多数答复者报告使用常见的马抗微生物药物（甲氧苄氨嘧啶（TMS）、青霉素和庆大霉素）。低和中等重要性的抗菌素主要用于牙齿和生殖疾病，尽管有一些高重要性药物的使用报告，包括一些未注册用于马的药物。开复方抗微生物药物的情况很常见（占应答者的70%）。据报道，抗菌剂也用于收缩肌腱、基质金属蛋白酶抑制、抗炎和抗内毒素以及其他非杀菌作用。结论：尽管抗菌素处方模式各不相同，但大多数应答者报告使用常见的马抗菌素。抗菌素指南可能有助于调整做法并减少马中不适当的抗菌素使用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Australian Veterinary Journal 农林科学-兽医学

CiteScore

2.40

自引率

0.00%

发文量

审稿时长

18-36 weeks

期刊介绍： Over the past 80 years, the Australian Veterinary Journal (AVJ) has been providing the veterinary profession with leading edge clinical and scientific research, case reports, reviews. news and timely coverage of industry issues. AJV is Australia''s premier veterinary science text and is distributed monthly to over 5,500 Australian Veterinary Association members and subscribers.