Choroidal Metastasis in Stage IV Lung Adenocarcinoma.

Beyoglu Eye Journal Pub Date : 2024-12-11 eCollection Date: 2024-01-01 DOI:10.14744/bej.2024.54871
Mehmet Icoz, Yelda Yildiz Tasci, Mucella Arikan Yorgun, Yasin Toklu
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Abstract

It is known that the incidence of lung cancer is increasing rapidly in both men and women. While no ocular findings may be observed in the early stage, ocular involvement may be observed in the advanced stage. The choroid is the most common site of intraocular metastasis in adults due to its rich vascularisation. In this report, a 52-year-old woman was referred to our clinic because of retinal detachment detected in an external center with complaints of flashes of light in the left eye 3 months ago and decreased vision for the past week. It was learned that she was diagnosed with advanced stage (stage IV) adenocarcinoma of the lung and received chemotherapy at regular intervals due to distant metastasis (liver and bone). Biomicroscopic fundus examination, B-Mode ultrasonography, fundus fluorescein angiography, and orbital magnetic resonance imaging revealed a choroidal mass. The current clinical picture was interpreted as distant metastasis of lung adenocarcinoma, no surgical intervention was planned for the secondary exudative retinal detachment, and the patient was consulted by the oncology clinic. In addition to chemotherapy, three cycles of radiotherapy were given within 1 week and the mass disappeared at the follow-up visit 2 months later. In the differential diagnosis of retinal detachment, metastasis of a diagnosed primary tumor should be considered as in our case. Early detection of these metastatic lesions and appropriate treatment strategies will prevent unnecessary vitreoretinal surgeries and complications.

肺腺癌 IV 期的脉络膜转移。
众所周知,肺癌的发病率在男性和女性中都在迅速增加。虽然在早期可能没有观察到眼部的发现,但在晚期可能会观察到眼部受累。脉络膜是成人眼内转移最常见的部位,因为它有丰富的血管。在本报告中,一名52岁女性因在外中心检测到视网膜脱离而被转介到我们诊所,3个月前她主诉左眼闪光,过去一周视力下降。据了解,她被诊断为晚期(IV期)肺腺癌,因远处转移(肝和骨),定期接受化疗。眼底生物显微镜检查、b超、眼底荧光素血管造影及眼眶核磁共振显示一脉络膜肿块。目前的临床表现解释为肺腺癌远处转移,继发性渗出性视网膜脱离未计划手术干预,患者咨询肿瘤诊所。除化疗外,1周内放疗3周期,2个月后随访肿块消失。在视网膜脱离的鉴别诊断中,原发肿瘤的转移应与本病例一样被考虑。这些转移性病变的早期发现和适当的治疗策略将防止不必要的玻璃体视网膜手术和并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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16 weeks
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