Back Cover: Jellyfish stings-induced cardiac failure was ameliorated through AAG-mediated glycogen-driven ATP production (EXP2 1/2025)

IF 22.5
Zhen Qin, Jinhong Chen, Fang Liu, Bingbing Li, Chenchen Zhang, Xiuxiu Wang, Lin Liu, Mingke Wang, Tingfang Wang, Su Wang, Feifei Yu, Shifeng Wang, Jishun Yang
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引用次数: 0

Abstract

Jellyfish stings have become a common injury among fishermen and divers. Severe jellyfish stings could worsen cardiac function and even cause cardiac complications, ultimately leading to cardiac failure (CF). Jellyfish stings-induced CF was ameliorated through AAG-mediated glycogen-driven ATP production, promoting glycolytic/mitochondrial metabolic switches to rely energetically primarily on glycolysis, which might serve as a therapeutic target of CF.

Abstract Image

后盖:水母蜇伤引起的心力衰竭通过aag介导的糖原驱动的ATP生成(EXP2 1/2025)得到改善
水母蜇伤已成为渔民和潜水员的常见伤害。严重的水母蜇伤会使心脏功能恶化,甚至引起心脏并发症,最终导致心力衰竭(CF)。水母蜇伤诱导的CF通过aag介导的糖原驱动的ATP生成得到改善,促进糖酵解/线粒体代谢开关主要依赖糖酵解,这可能是CF的治疗靶点。
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