Gut–X axis

IF 23.7 Q1 MICROBIOLOGY
iMeta Pub Date : 2025-02-26 DOI:10.1002/imt2.270
Xu Lin, Zuxiang Yu, Yang Liu, Changzhou Li, Hui Hu, Jia-Chun Hu, Mian Liu, Qin Yang, Peng Gu, Jiaxin Li, Kutty Selva Nandakumar, Gaofei Hu, Qi Zhang, Xinyu Chen, Huihui Ma, Wenye Huang, Gaofeng Wang, Yan Wang, Liping Huang, Wenjuan Wu, Ning-Ning Liu, Chenhong Zhang, Xingyin Liu, Leming Zheng, Peng Chen
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Abstract

Recent advances in understanding the modulatory functions of gut and gut microbiota on human diseases facilitated our focused attention on the contribution of the gut to the pathophysiological alterations of many extraintestinal organs, including the liver, heart, brain, lungs, kidneys, bone, skin, reproductive, and endocrine systems. In this review, we applied the “gut–X axis” concept to describe the linkages between the gut and other organs and discussed the latest findings related to the “gut–X axis,” including the underlying modulatory mechanisms and potential clinical intervention strategies.

Abstract Image

Gut-X轴
最近对肠道和肠道微生物群对人类疾病的调节功能的理解取得了进展,这有助于我们将注意力集中在肠道对许多肠外器官的病理生理改变的贡献上,包括肝、心、脑、肺、肾、骨、皮肤、生殖和内分泌系统。在这篇综述中,我们应用“肠- x轴”概念来描述肠道与其他器官之间的联系,并讨论了与“肠- x轴”相关的最新发现,包括潜在的调节机制和潜在的临床干预策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
10.80
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