Characterization of Particles From Collagen Bio-Stimulating Materials Used in Facial Filling Procedures.

IF 2 3区工程技术 Q2 ANATOMY & MORPHOLOGY

Microscopy Research and Technique Pub Date : 2025-02-24 DOI:10.1002/jemt.24837

Marina de Moraes Nobre, May Anny Alves Fraga, Valéria Dal Coll, Cássia Almeida Brito, Livia Rodrigues de Menezes, Marcela Marçal Thebit, Américo Bortolazzo Correr

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引用次数: 0

Abstract

The aim of this study was to characterize the calcium hydroxyapatite (CaHA) particles present in collagen bio-stimulating materials used in facial rejuvenation procedures. Five collagen bio-stimulating materials were evaluated: Radiesse, Rennova Diamond, HarmonyCa, Victalab Bio-stimulator, and Optimus Bio-stimulator. One gram of each material was successively immersed in water to remove the organic part (carboxymethyl cellulose) until the supernatant was clear. Particle morphology and composition were analyzed by scanning electron microscopy (SEM), energy dispersive x-ray microanalysis (EDX) and Fourier transform infrared spectroscopy (FTIR). Radiesse showed particles with homogeneous distribution, spherical shape, and size between 24 and 38 μm. Rennova Diamond and HarmonyCa had a spherical shape and varied sizes, between 12-62 μm and 22-51 μm, respectively. Victalab and Optimus showed irregular particles, sharp angles, and sizes between 3-93 μm and 4-57 μm, respectively. FTIR analyzes showed that all materials presented CaHA with similar composition. It can be concluded that the collagen bio-stimulator materials presented different inorganic contents in terms of size and morphology.

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来源期刊

Microscopy Research and Technique 医学-解剖学与形态学

CiteScore

5.30

自引率

20.00%

发文量

233

审稿时长

4.7 months

期刊介绍： Microscopy Research and Technique (MRT) publishes articles on all aspects of advanced microscopy original architecture and methodologies with applications in the biological, clinical, chemical, and materials sciences. Original basic and applied research as well as technical papers dealing with the various subsets of microscopy are encouraged. MRT is the right form for those developing new microscopy methods or using the microscope to answer key questions in basic and applied research.