Ulva Seaweed-Derived Ulvan: A Promising Marine Polysaccharide as a Sustainable Resource for Biomaterial Design.

IF 4.9 2区医学 Q1 CHEMISTRY, MEDICINAL

Marine Drugs Pub Date : 2025-01-24 DOI:10.3390/md23020056

Rizfi Fariz Pari, Uju Uju, Safrina Dyah Hardiningtyas, Wahyu Ramadhan, Rie Wakabayashi, Masahiro Goto, Noriho Kamiya

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引用次数: 0

Abstract

Green seaweed is currently underused compared with other major seaweed types. Many scientists have reported applications of the green seaweed Ulva in various fields in recent years, which makes it a candidate for biomass production in industrial biorefineries. Ulva contains a unique polysaccharide called ulvan, which is being considered for medicinal and pharmacological applications. Ulvan is a sulfated polysaccharide including rhamnose and glucuronic acid residues, which has a range of bioactivities, including immunomodulatory, antimicrobial, and anticoagulant properties. The biocompatibility of ulvan makes it a versatile candidate for biomaterial design. This review presents an in-depth analysis of the potential applications of ulvan, starting with extraction methods and structural/biological characterization and moving on to biomaterial design. We also highlight the advantages of ulvan over traditional seaweed polysaccharides such as agar, carrageenan, and alginate.

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海藻衍生的Ulvan：一种有前途的海洋多糖作为生物材料设计的可持续资源。

与其他主要海藻类型相比，绿海藻目前未得到充分利用。近年来，许多科学家报道了绿海藻Ulva在各个领域的应用，这使得它成为工业生物炼制生物质生产的候选物。Ulva含有一种称为ulvan的独特多糖，正在考虑用于医学和药理学应用。Ulvan是一种含鼠李糖和葡萄糖醛酸残基的硫酸酸化多糖，具有一系列生物活性，包括免疫调节、抗菌和抗凝血性能。ulvan的生物相容性使其成为生物材料设计的通用候选材料。本文综述了ulvan的潜在应用，从提取方法和结构/生物学表征开始，再到生物材料的设计。我们还强调了ulvan比传统海藻多糖（如琼脂、卡拉胶和海藻酸盐）的优势。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Marine Drugs 医学-医药化学

CiteScore

9.60

自引率

14.80%

发文量

671

审稿时长

1 months

期刊介绍： Marine Drugs (ISSN 1660-3397) publishes reviews, regular research papers and short notes on the research, development and production of drugs from the sea. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible, particularly synthetic procedures and characterization information for bioactive compounds. There is no restriction on the length of the experimental section.